Drivers of melioidosis endemicity: epidemiological transition, zoonosis, and climate change. [PDF]
Curr Opin Infect Dis, 2022 Birnie E, Biemond JJ, Wiersinga WJ.
europepmc +1 more source
Advanced Science, EarlyView.Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go +12 more
wiley +1 more source
The Global Epidemiological Transition in Cardiovascular Diseases: Unrecognised Impact of Endemic Infections on Peripheral Artery Disease. [PDF]
J Epidemiol Glob Health, 2022 Agius PA +9 more
europepmc +1 more source
Epidemiology in transition [PDF]
International Journal of Epidemiology, 1999 openaire +2 more sources
Advanced Science, EarlyView.This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang +10 more
wiley +1 more source
Utility of silhouette showcards to assess adiposity in three countries across the epidemiological transition. [PDF]
PLOS Glob Public Health, 2022 Reese TO +14 more
europepmc +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Epidemiological transition to mortality and refracture following an initial fracture. [PDF]
Elife, 2021 Ho-Le TP +7 more
europepmc +1 more source
Advanced Science, EarlyView.Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao +11 more
wiley +1 more source
Temporal trends in the burden of non-communicable diseases in countries with the highest malaria burden, 1990-2019: Evaluating the double burden of non-communicable and communicable diseases in epidemiological transition. [PDF]
Global Health, 2022 Li Z +5 more
europepmc +1 more source