Results 201 to 210 of about 2,787,964 (309)

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

Advanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han, Qin Yuan, Zhu Wu, Yaohui Fang, Hong Qian, Jiale Zhu, Yuchen Zhang, Ke Deng, Liangliang Su, Haibo Xu, Haotian Shu, Yiming Gong, Qiaoqiao Xu, Guizhen Du, Di Wu, Yun Fan, Chuncheng Lu   +16 more
wiley   +1 more source

Some questions of epidemiology and diagnostics of osteoporosis.

, 2018
S. Issayeva
openalex   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Is Digital Epidemiology the Future of Clinical Epidemiology?

Journal of Epidemiology and Global Health, 2019
Giuseppe Lippi, Camilla Mattiuzzi, Gianfranco Cervellin   +2 more
doaj   +1 more source

Correction: Association between trait mindfulness and self-efficacy in sports-disadvantaged college students in China: the chain mediating role of exercise motivation and persistence. [PDF]

Front Psychol
Xu K, Zhu L, Li Y, Cao Y, Zhang G.
europepmc   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

Rapid expansion of the Frontline Field Epidemiology Training Program across 124 districts in India, 2021-2023. [PDF]

Health Res Policy Syst
Dhuria M, VanderEnde K, Tanwar S, Vaze A, Yadav S, Choudhary S, Yadav R, Desai M, Bahl A, Jain SK, Singh SK, Chauhan H, Goel A.   +12 more
europepmc   +1 more source

Epidemiology of cutaneous Leishmaniosis in south Fars province, Iran: A retrospective decade long survey

, 2020
Mohammad-Rafi Bazrafshan, Khalil Safari, Nasrin Shokrpour, Hamed Delam   +3 more
openalex   +2 more sources

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Correction: Prediction models for different types of leukemia: a systematic review and critical appraisal. [PDF]

J Cancer Res Clin Oncol
Tuerxun A, Yang Y, Cai X, Chen X, Zhao Z, Zhao Y, Lin Z, Wang S.   +7 more
europepmc   +1 more source