Results 141 to 150 of about 2,146,866 (353)

Avaliação dos indicadores epidemiológicos e operacionais para a hanseníase em municípios prioritários no estado do Paraná, 2001 a 2010

Epidemiologia e Serviços de Saúde
OBJETIVO: descrever os indicadores epidemiológicos e operacionais da hanseníase nos municípios de Curitiba, Londrina e Foz do Iguaçu, estado do Paraná, Brasil.
Keurilene Sutil de Oliveira, Jhenifer de Souza, Regiane Bezerra Campos, Adriana Zilly, Reinaldo Antonio Silva-Sobrinho   +4 more
doaj   +1 more source

Descriptive Epidemiology of Soil-Transmitted Helminth Infections in the United States: Using Big Data to Characterize Patients and Analyze Parasitic Disease Trends [PDF]

Chad L. Cross, Bryson Carrier, María José Fernández Alcalá, Louisa A. Messenger   +3 more
openalex   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Descriptive Epidemiology of Collegiate Women's Gymnastics Injuries: National Collegiate Athletic Association Injury Surveillance System, 1988–1989 Through 2003–2004

, 2020
Stephen W. Marshall
openalex   +1 more source

The First Decade of Web-Based Sports Injury Surveillance: Descriptive Epidemiology of Injuries in United States High School Football (2005–2006 Through 2013–2014) and National Collegiate Athletic Association Football (2004–2005 Through 2013–2014) [PDF]

, 2018
Zachary Y. Kerr, Gary B. Wilkerson, Shane V. Caswell, Dustin W. Currie, Lauren A. Pierpoint, Erin B. Wasserman, Sarah B. Knowles, Thomas P. Dompier, R. Dawn Comstock, Stephen W. Marshall   +9 more
openalex   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Descriptive epidemiology of malignant mesothelioma.

La Medicina del lavoro, 2005
Malignant mesothelioma (MM) is a rare cancer associated with exposure to asbestos, whose occurrence is increasing in industrialized countries.Describe and discuss: determinant factors, natural history, epidemic pattern, burden of MM to society at large, where interventions should be directed to change MM occurrence, gaps in knowledge.Review of the ...
openaire   +2 more sources