Results 151 to 160 of about 548,075 (306)

Bovine neonatal pancytopenia: descriptive epidemiology in Belgium [PDF]

, 2010
Callens, Jozefien, De Bleecker, Koen, De Clercq, Kris, Deprez, Piet, Dierick, Jan, Ducatelle, Richard, Maes, Sofie, Pardon, Bart, Saey, Veronique, Steukers, Lennert, Vercauteren, Griet   +10 more
core  

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Editorial: Epidemiology of orthopaedic sports trauma and injuries. [PDF]

Front Sports Act Living
Hoveidaei AH, Parker J, Razi M, Ritzmann R, Adolf J, Tabaie SA.   +5 more
europepmc   +1 more source

The epidemiology of patellar luxation in dogs attending primary-care veterinary practices in England [PDF]

, 2016
A Blaney, A Edney, A Egenvall, AG Hayes, AL Johnson, B Vidoni, BR Kirkwood, C Soparat, C Wangdee, C Wangdee, C Wangdee, CA Campbell, CL Fitzpatrick, D Hulse, D O'Neill, DG O'Neill, DG O'Neill, DN Irion, DW Hosmer, E Comerford, E LaFond, FE Taylor-Brown, GC Knight, GI Arthurs, I Dohoo, IC Lavrijsen, J Coresh, JK Roush, K Fujii, K Nagaoka, K Soontornvipart, L Asher, LM Collins, LM Collins, M DeAngelis, M Ness, MR Alam, N Bound, P Bateson, PC Bartlett, R Daems, RE Wolf, RG Roy, S Gibbons, S Kalff, S Pinna, S Shoop, SFJ Hodgman, WA Priester, WR Linney   +49 more
core   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Moving From Representativeness Toward Transportability in an Era of Digital and Big Data. [PDF]

Int J Public Health
Chiolero A.
europepmc   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

Advanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen   +17 more
wiley   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Lessons learned from Okinawa, Japan underscore the importance of clinical epidemiology in COVID-19 prevention and control. [PDF]

Environ Health Prev Med
Kishimoto T, Tasato D, Nagasawa Y, Yamashiro A, Shokita H.   +4 more
europepmc   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source