Results 41 to 50 of about 61,018 (259)

In Vitro Fertility of Post-thawed Epididymal Ram Spermatozoa After Storage at 5 °C Before Cryopreservation [PDF]

open access: yes, 2013
This study addressed the effects of storage duration of epididymides at 5 °C before sperm collection and their fertility after cryopreservation in vitro.
fahrudin, M. (M)   +2 more
core  

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Regulation of epithelial function, differentiation, and remodeling in the epididymis

open access: yesAsian Journal of Andrology, 2016
The epididymis is a single convoluted tubule lined by a pseudostratified epithelium. Specialized epididymal epithelial cells, the so-called principal, basal, narrow, and clear cells, establish a unique luminal environment for the maturation and storage ...
Sylvie Breton   +3 more
doaj   +1 more source

Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy. [PDF]

open access: yes, 2019
Maternal recognition of pregnancy (MRP) in the mare is not well defined. In a non-pregnant mare, prostaglandin F2α (PGF) is released on day 14 post-ovulation (PO) to cause luteal regression, resulting in loss of progesterone production. Equine MRP occurs
Bouma, Gerrit J   +10 more
core   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma   +17 more
wiley   +1 more source

The significance of single-cell transcriptome analysis in epididymis research

open access: yesFrontiers in Cell and Developmental Biology
As a crucial component of the male reproductive system, the epididymis plays multiple roles, including sperm storage and secretion of nutritive fluids for sperm development and maturation.
Meng-Meng Liu   +4 more
doaj   +1 more source

Canine and Feline Epididymal Semen—A Plentiful Source of Gametes

open access: yesAnimals, 2021
Canine and feline epididymal semen provide an additional source of gametes to preserve the genetics of valuable breeding dogs and tomcats, especially for those that fail to ejaculate, need castration as a therapy or die unexpectedly.
Hiba Ali Hassan   +5 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Epididymal Leiomyoadenomatoid Tumour: A Rare Case Report and Literature Review

open access: yesJournal of Urological Surgery, 2021
Adenomatoid tumours are benign neoplasms of mesothelial origin that most often occur in the epididymis in men and the uterus or fallopian tubes in women.
Fatih Yılmaz   +4 more
doaj   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma   +28 more
wiley   +1 more source

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