Results 51 to 60 of about 66,714 (321)

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

The significance of single-cell transcriptome analysis in epididymis research

Frontiers in Cell and Developmental Biology
As a crucial component of the male reproductive system, the epididymis plays multiple roles, including sperm storage and secretion of nutritive fluids for sperm development and maturation.
Meng-Meng Liu, Xin-Lei Feng, Chao Qi, Shu-Er Zhang, Guo-Liang Zhang   +4 more
doaj   +1 more source

Effect of alcoholic extract of soy bean consumption by pregnant mice on the testis and epididymis of their male offspring's

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2013
Soy is flavones are phytoestrogens with potential hormonal activity due to their similar chemical structure to 17-B-estradiol. The increasing availability of Soy is flavones throughout the food supply and through use of supplements has prompted ...
Abeer Salih Ali, Nisreen Khazal Flayyih, Hadeel Mohammed Qasim   +2 more
doaj   +1 more source

Seasonal expressions of SPAG11A and androgen receptor in the epididymis of the wild ground squirrels (Citellus dauricus Brandt)

European Journal of Histochemistry, 2020
Sperm-associated antigen 11A (SPAG11A) is expressed exclusively in the epididymis, which can specifically regulate sperm maturation. The aim of this study was to investigate the seasonal expressions of beta-defensin (SPAG11A) and androgen receptor (AR ...
Wenyang Yu, Ziwen Zhang, Pei Liu, Xiaoying Yang, Haolin Zhang, Zhengrong Yuan, Yingying Han, Qiang Weng   +7 more
doaj   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]

, 2011
The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
core  

Machine Learning‐Enhanced Analysis of Exosomal Surface Sialic Acid Using Surface‐Enhanced Raman Spectroscopy for Ovarian Cancer Diagnosis and Therapeutic Monitoring

Advanced Science, EarlyView.
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong, Jiaqi Wang, Sijun Huang, Xiaxia Man, Yi Guo, Shuping Xu, Songling Zhang   +6 more
wiley   +1 more source

Monthly changes in testes and epididymis measurements with some semen characteristics of tail epididymis for Iraqi buffalo

The Iraqi Journal of Veterinary Medicine, 2012
The present study was carried out to investigate the reproductive activity of mature buffalo bull and months changes on the testes and epididymis. Two hundred and fifty ( 250) testes of mature buffalo bull were collected from the slaughter house east ...
Mohammed Mehdi AL-Sahaf
doaj   +1 more source

Aquaporins Are Differentially Regulated in Canine Cryptorchid Efferent Ductules and Epididymis

Animals, 2021
The efferent ductules and the epididymis are parts of the male reproductive system where spermatozoa mature. Specialized epithelial cells in these ducts contribute to the transport of fluids produced by spermatozoa’s metabolic activity. Aquaporins (AQPs)
Caterina Squillacioti, Nicola Mirabella, Giovanna Liguori, Giuseppe Germano, Alessandra Pelagalli   +4 more
doaj   +1 more source