Results 191 to 200 of about 43,158 (291)

Very Long‐Term Follow‐Up of Multidimensional Health‐Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study

open access: yesHead &Neck, Volume 48, Issue 4, Page 1088-1096, April 2026.
ABSTRACT Background To evaluate postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients, multidimensional assessment is important. Available data is limited on long‐term follow‐up. Methods Prospectively, 52 nonfunctioning (NFA) and functioning (FA) pituitary adenoma patients were included.
Gonneke E. Joustra   +7 more
wiley   +1 more source

Erector spinae plane block versus caudal epidural block in pediatric surgery: a systematic review and meta-analysis of randomized clinical trials. [PDF]

open access: yesBraz J Anesthesiol
Masiero BB   +13 more
europepmc   +1 more source

The association between epidural analgesia and perineal injury in primiparous women: A propensity score‐matched cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 173, Issue 1, Page 144-150, April 2026.
Abstract Objective To determine the association between epidural analgesia and perineal injury, including obstetric anal sphincter injury (OASI), in primiparous women. Methods We conducted a retrospective cohort study of primiparous women with singleton, term, vertex, and vaginal deliveries between 2012 and 2024 at a tertiary medical center.
Omri Dominsky   +6 more
wiley   +1 more source

Premixed Lidocaine With Fospropofol Disodium for Safety and Clinical Evaluation Regarding Paresthesia Upon Fospropofol Disodium Injection: A Preclinical Experimental Study and a Randomized Controlled Trial

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This study explored the effect of lidocaine premixing on fospropofol‐induced paresthesia. While the mixture of fospropofol (FP) and lidocaine (LD) proved chemically stable and safe in preclinical tests, clinical results from randomized controlled trial showed no reduction in paresthesia in FP+LD group compared with FP+NS group.
Bo Jiao   +17 more
wiley   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

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