Results 231 to 240 of about 25,048 (287)

PGC‐1α Transcriptionally Regulated by ChREBP Mitigates Neuropathic Pain Through Promoting Microglial Fatty Acid Oxidation and Anti‐Inflammatory Response

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
ChREBP transcriptionally regulates PGC‐1α, which enhances the expression of fatty acid oxidation genes, promotes the fatty acid oxidation process, and thereby increases the polarization of anti‐inflammatory microglia, reduces the level of inflammatory factors, and improves pain symptoms.
Ziwei Hu, Jiahui Pang, Xinli Liu, Yun Zhao, Yi Lu, Hui Chen, Hui Zeng, Youxin Yu, Yubai Zhao, Lijie Gao, Xuefei Zhang, Jian Jin, Kangling Wang, Yu Shi, Hongrui Zhan, Wen Wu   +15 more
wiley   +1 more source

Comparison of Ultrasound-guided Bilateral Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament with Conventional Epidural Block in Patients Undergoing Laparoscopic Radical Gastrectomy: A Randomized Controlled Study. [PDF]

J Med Ultrasound
Lin L, Yu Y, Ke P, Liu L, Wu Q, Lin Q.
europepmc   +1 more source

Manual versus forceps postplacental IUD insertion after vaginal delivery: A randomized clinical trial

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 510-517, January 2026.
Abstract Objectives This study compares the expulsion rate of the postplacental copper intrauterine device (IUD) based on the insertion technique: manual versus ring forceps. Pain, perforation, infection, and increased bleeding were assessed as secondary outcomes.
Thuany Bento Herculano, Andressa Aparecida Luciano Batista, Cássia Raquel Teatin Juliato, Patrícia Moretti Rehder, Fernanda Surita   +4 more
wiley   +1 more source

Increased lumbar puncture success using a paramedian approach: A retrospective cohort study

Journal of Hospital Medicine, Volume 21, Issue 1, Page 42-48, January 2026.
Abstract Background Lumbar puncture (LP) is frequently necessary in hospitalized patients for diagnostic and therapeutic purposes. Traditional landmark identification by palpation of the lumbar spine and pelvis can see significant failure rates. A paramedian approach is an accepted, though less frequently used technique associated with higher success ...
Jacob Wagner, Kiril Dimitrov, Zachary Lauer, Swati Jain, Omar Jibril, Zach Kaltenborn, Aditya Kler, Andrew Olson, Justin Clark, Kyle Rudser, Matthew Yocum   +10 more
wiley   +1 more source

Pharmacological Inhibition of EZH2 by GSK‐343 Attenuates Neuroinflammation in a Mouse Model of Spinal Cord Injury

Journal of Neuroscience Research, Volume 104, Issue 1, January 2026.
In a mouse model of spinal cord injury, pharmacological inhibition of EZH2 with GSK‐343 reduces tissue damage and neuronal demyelination. GSK‐343 suppresses the EZH2/TRAF6/NF‐κB signaling pathway, leading to attenuation of neuroinflammation and innate immune activation. These effects promote early neuroprotection and improved locomotor recovery in vivo.
Yinhui Kang, Deborah Mannino, Valentina Bova, Alberto Repici, Bulzomì Maria, Ahmed Hasan, Antonio Catalfamo, Jia Yang, Marika Lanza, Alessia Filippone   +9 more
wiley   +1 more source

Impact of Environmental and Seasonal Factors on Spontaneous Pneumomediastinum With and Without Pneumorrhachis

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 1, January 2026.
ABSTRACT Spontaneous pneumomediastinum (SPM) with pneumorrhachis is rare but generally benign and self‐limiting. However, the impact of environmental and seasonal factors on SPM remains unclear. This study investigated their association with SPM onset and clinical outcomes.
Yu‐Wei Liu, Chieh‐Ni Kao, Chi‐Chang Ho, Shah‐Hwa Chou, Pau‐Chung Chen, Shu‐Hung Huang   +5 more
wiley   +1 more source

Summary of Evidence for Perioperative Management of Day Surgery Patients Undergoing Anorectal Surgery

Nursing Open, Volume 13, Issue 1, January 2026.
ABSTRACT Aim This scoping review aimed to map and synthesise the available evidence on the perioperative management of patients undergoing anorectal surgery in a day‐surgery setting. This study creates the first unified, evidence‐based framework for day‐surgery anorectal care.
Yahui Gao, Mindan Wang, Yingying Jiang
wiley   +1 more source

The analgesic efficacy of ultrasound-guided erector spinae plane block versus ultrasound-guided caudal epidural block for abdominal surgery in pediatric patients - A patient and assessor-blind, randomized controlled study. [PDF]

Saudi J Anaesth
Pandey A, Ahmad Z, Jain S, Pakhare A, Sharma PK, Waindeskar V, Mandal P, Karna ST.   +7 more
europepmc   +1 more source

Pharmacotherapeutic Controversies During Temperature Control After Out‐of‐Hospital Cardiac Arrest: A Semi‐Structured Literature Review

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 1, January 2026.
ABSTRACT Post‐resuscitation cardiac arrest care begins at the time of hospital admission and focuses on preventing the sequelae of ischemia–reperfusion injury, including secondary brain damage and post‐cardiac arrest syndrome. Clinical practice guidelines on post‐resuscitation cardiac arrest care from international medical organizations outline ...
Christy Cecil Forehand, Scott Thomas Benken, Melanie Madorsky, Adham Mohamed, Jerika V. Nguyễn, Deepali Dixit, Jolie Gallagher, William Anthony Hawkins, Mojdeh Saba Heavner, Emory Johnson, Lauren Lozano, Melanie Sisco, Angela A. Slampak‐Cindric, Susan Elizabeth Smith, Katherine Spezzano, Bayard Angel Taylor II, Nathaniel Brett Wayne, David John Gagnon   +17 more
wiley   +1 more source

The psychological impact of childbirth: Unscheduled cesarean delivery associates with increased risk for acute stress response

Pregnancy, Volume 2, Issue 1, January 2026.
Abstract Introduction Cesarean delivery is one of the most common surgical procedures in the United States. Despite their frequency and medical necessity, the acute psychological response associated with unscheduled cesarean delivery is unknown. This study aimed to assess the rates and nature of peritraumatic stress reactions during and shortly after ...
Hadas Allouche‐Kam, Isha Hemant Arora, Christina T. Pham, Eunice Chon, Mary Lee, Onyekachi Agwu, Jiajia Zhang, Evelyn Milavsky, Andrea G. Edlow, Francine Hughes, Scott P. Orr, Anjali J. Kaimal, Sharon Dekel   +12 more
wiley   +1 more source