Results 41 to 50 of about 34,722 (203)
BackgroundParkinson’s disease (PD) is a complex neurodegenerative disease with an elusive etiology that involves the interaction between genetic, behavioral, and environmental factors.
Yen-Chung Chen +10 more
doaj +1 more source
Kant's Metaphysics of Race, Its Distinctiveness, and Its Normativity
ABSTRACT Drawing on the contemporary taxonomy of the metaphysics of race, this paper shows that Kant's theory of race occupies a distinct metaphysical position on race. Second, it argues that Kant's metaphysics of race inherently produces racist claims.
Reza Mosayebi
wiley +1 more source
Epigenetic associations of GPNMB rs199347 variant with alcohol consumption in Parkinson’s disease
IntroductionAlcohol consumption can induce a neuroinflammatory response and contribute to the progression of neurodegeneration. However, its association with Parkinson’s disease (PD), the second most common neurodegenerative disorder, remains ...
Yen-Chung Chen +10 more
doaj +1 more source
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green +2 more
wiley +1 more source
Epigênese e epigenética: as muitas vidas do vitalismo ocidental
Resumo A análise da história e dos usos contemporâneos dos termos epigênese, atribuído a Aristóteles, e epigenética, criado no século XX pelo biólogo C. H.
Gláucia Silva +1 more
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Epigenetics—Innovations and Misconceptions
ABSTRACT Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in the regulation and perpetuation of gene activity states.
Bernhard Horsthemke
wiley +1 more source
We present results from petrographic and lithogeochemical studies of the Late Precambrian terrigenous rocks (sandstones, gravelites, and aleuritic sandstones) from the Oselkovaya series of Prisayanie. The studies were conducted to reconstruct the primary
Z. L. Motova +2 more
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Mitochondria and metazoan epigenesis [PDF]
In eukaryotes, mitochondrial activity controls ATP production, calcium dynamics, and redox state, thereby establishing physiological parameters governing the transduction of biochemical signals that regulate nuclear gene expression. However, these activities are commonly assumed to fulfill a 'housekeeping' function: necessary for life, but an ...
openaire +2 more sources
Exopolymeric substances (EPS) produced in the photic zone and surface sediments sequester calcium. Below the sediment surface, heterotrophic bacteria degrade EPS, releasing calcium resulting in carbonate precipitation. This process, which continues for millennia deep in the core, is an important sink for atmospheric carbon dioxide.
Pieter T. Visscher +9 more
wiley +1 more source
En el trabajo mostramos que la matriz conceptual utilizada por I. Kant en su concepción de la historia universal en su texto Idea de una historia universal en sentido cosmopolita es la misma mediante la cual el filósofo da cuenta de la producción de ...
Natalia Lerussi
doaj +1 more source

