Results 41 to 50 of about 34,722 (203)

Epigenetic regulation of Parkinson’s disease risk variant GPNMB cg17274742 methylation by sex and exercise from Taiwan Biobank

open access: yesFrontiers in Aging Neuroscience, 2023
BackgroundParkinson’s disease (PD) is a complex neurodegenerative disease with an elusive etiology that involves the interaction between genetic, behavioral, and environmental factors.
Yen-Chung Chen   +10 more
doaj   +1 more source

Kant's Metaphysics of Race, Its Distinctiveness, and Its Normativity

open access: yesJournal of Social Philosophy, Volume 57, Issue 3, Page 374-386, Fall 2026.
ABSTRACT Drawing on the contemporary taxonomy of the metaphysics of race, this paper shows that Kant's theory of race occupies a distinct metaphysical position on race. Second, it argues that Kant's metaphysics of race inherently produces racist claims.
Reza Mosayebi
wiley   +1 more source

Epigenetic associations of GPNMB rs199347 variant with alcohol consumption in Parkinson’s disease

open access: yesFrontiers in Psychiatry
IntroductionAlcohol consumption can induce a neuroinflammatory response and contribute to the progression of neurodegeneration. However, its association with Parkinson’s disease (PD), the second most common neurodegenerative disorder, remains ...
Yen-Chung Chen   +10 more
doaj   +1 more source

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 270-290, June 2026.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green   +2 more
wiley   +1 more source

Epigênese e epigenética: as muitas vidas do vitalismo ocidental

open access: yesHorizontes Antropológicos
Resumo A análise da história e dos usos contemporâneos dos termos epigênese, atribuído a Aristóteles, e epigenética, criado no século XX pelo biólogo C. H.
Gláucia Silva   +1 more
doaj   +1 more source

Epigenetics—Innovations and Misconceptions

open access: yesNatural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in the regulation and perpetuation of gene activity states.
Bernhard Horsthemke
wiley   +1 more source

THE COMPOSITION AND RECONSTRUCTION OF THE SOURCE AREA FOR THE LATE PRECAMBRIAN TERRIGENOUS ROCKS OF THE OSELKOVAYA SERIES (BIRYUSA PRISAYANIE)

open access: yesГеодинамика и тектонофизика, 2016
We present results from petrographic and lithogeochemical studies of the Late Precambrian terrigenous rocks (sandstones, gravelites, and aleuritic sandstones) from the Oselkovaya series of Prisayanie. The studies were conducted to reconstruct the primary
Z. L. Motova   +2 more
doaj   +1 more source

Mitochondria and metazoan epigenesis [PDF]

open access: yesSeminars in Cell & Developmental Biology, 2009
In eukaryotes, mitochondrial activity controls ATP production, calcium dynamics, and redox state, thereby establishing physiological parameters governing the transduction of biochemical signals that regulate nuclear gene expression. However, these activities are commonly assumed to fulfill a 'housekeeping' function: necessary for life, but an ...
openaire   +2 more sources

A critical role of heterotrophic bacteria in early diagenesis of carbonates through exopolymer degradation and calcium release

open access: yesThe Depositional Record, Volume 12, Issue 1, February 2026.
Exopolymeric substances (EPS) produced in the photic zone and surface sediments sequester calcium. Below the sediment surface, heterotrophic bacteria degrade EPS, releasing calcium resulting in carbonate precipitation. This process, which continues for millennia deep in the core, is an important sink for atmospheric carbon dioxide.
Pieter T. Visscher   +9 more
wiley   +1 more source

Acerca de una consideración naturalizada de la filosofía de la historia de Immanuel Kant: Epigénesis e historia universal

open access: yesCadernos de Filosofia Alemã, 2015
En el trabajo mostramos que la matriz conceptual utilizada por I. Kant en su concepción de la historia universal en su texto Idea de una historia universal en sentido cosmopolita es la misma mediante la cual el filósofo da cuenta de la producción de ...
Natalia Lerussi
doaj   +1 more source

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