Results 21 to 30 of about 11,842 (158)

Systematic statistical analysis of change in SEIzure interVAL with diazepam nasal spray supports this novel clinical endpoint for immediate‐use seizure medication

open access: yesEpilepsia, EarlyView.
Abstract Objective Appropriate endpoints for daily antiseizure medications may differ from those for intermittent, immediate‐use seizure medications (ISMs). The observed interval between seizure clusters over time (SEIzure interVAL [SEIVAL]) has been proposed as a novel effectiveness endpoint for ISMs.
Wesley T. Kerr   +4 more
wiley   +1 more source

Listening across frequencies: Capturing seizures of all patients to advance antiseizure medication development

open access: yesEpilepsia, EarlyView.
Abstract Seizure frequency has been the primary endpoint in epilepsy trials, with enrollment usually requiring ≥4 seizures per month. This threshold is more and more misaligned with clinical reality, as the availability of more treatment options has reduced baseline seizure burden, with a risk of excluding a proportion of patients from trials. Although
Stéphane Auvin, Jacqueline French
wiley   +1 more source

Predicting seizure freedom in the postpartum period: Findings from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs study

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether seizure freedom in pregnancy predicts seizure freedom in the postpartum period in women with epilepsy (WWE). Prior studies have shown that seizure freedom prior to conception strongly predicts seizure freedom during pregnancy.
Emma C. Osterhaus   +7 more
wiley   +1 more source

Una Institución Médico-Educativa para Rehabilitación de Personas con Epilepsia. Fundada En 1975 en Cartagena de India

open access: yesMedicina, 2009
<h3>Resumen</h3><p><em><span>Objetivo</span>: Presentar nuestra experiencia como el primer centro en América Latina para rehabilitar personas con epilepsia y trastornos del aprendizaje.
M. Córdoba   +5 more
doaj  

Epilepsia

open access: yesRevista Neurociências, 1993
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openaire   +2 more sources

Low diagnostic yield of presurgical genetic testing in adult patients with epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine the diagnostic yield of genetic testing in patients undergoing presurgical evaluation for epilepsy. Methods We conducted a cohort study including 115 adult patients who underwent presurgical evaluation in the Calgary Epilepsy Program between 2019 and 2023 and who had undergone research exome sequencing.
Clara Jünemann   +16 more
wiley   +1 more source

Cognitive and behavioral clinical outcome assessments in children with developmental and epileptic encephalopathies: Issues and instruments

open access: yesEpilepsia, EarlyView.
Abstract Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized.
Cinzia Correale   +9 more
wiley   +1 more source

Caracterización de Los Problemas de Aprendizaje en Niños y Adolescentes con Epilepsia Primaria Generalizada en La Liga Central contra la Epilepsia y El Hospital de la Misericordia (Bogotá, Colombia)*

open access: yesMedicina, 2011
<p><strong>* Trabajo ganador del Premio Nacional a la Investigación e Epilepsia Margaret Merz de Fandiño 2011. </strong></p><h4>RESUMEN</h4><p><span>Objetivo:</span> Determinar la prevalencia de los ...
Lina Marcela Tavera Saldaña   +5 more
doaj  

Uso de la electroencefalografía urgente por el neurólogo de guardia: utilidad en el diagnóstico del estatus epiléptico no convulsivo

open access: yesNeurología, 2018
Resumen: Introducción: Estudio que describe la experiencia en el uso del electroencefalograma urgente (EEGurg) por la guardia de neurología ante la sospecha de estatus epiléptico no convulsivo (EENC) y en otras indicaciones en un hospital terciario ...
J.U. Máñez Miró   +3 more
doaj   +1 more source

Diagnosis and management guidelines for infantile epileptic spasms syndrome around the world: A scoping review and comparative study of international approaches

open access: yesEpilepsia, EarlyView.
Abstract Objective Infantile epileptic spasms syndrome (IESS) is an epileptic encephalopathy requiring rapid diagnosis and treatment to optimize neurodevelopmental outcomes. Although multiple national and regional guidelines exist, recommendations vary.
Gozde Erdemir   +21 more
wiley   +1 more source

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