Results 61 to 70 of about 99,774 (210)

Long-term surgical outcomes in patients with drug-resistant temporal lobe epilepsy and no histological abnormalities

Neurología (English Edition), 2013
Introduction: Reports on surgical outcomes in patients with drug-resistant temporal lobe epilepsy without histological abnormalities are scarce. Methods: Retrospective review of data from patients with drug-resistant temporal lobe epilepsy and no ...
J.C. Benedetti-Isaac, M. Torres-Zambrano, J. Fandiño-Franky, J. Dussán-Ordóñez, A. Herrera-Trujillo, R. Guerra-Olivares, G. Alcalá-Cerra   +6 more
doaj   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]

, 2018
The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
core   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Effectiveness of minority public relations: the case of the Epilepsy Association of the Province of Alicante (EAPA) [PDF]

, 2013
La Asociación de Epilepsia de la Provincia de Alicante (AEPA) implementa su estrategia de relaciones públicas concibiendo a los públicos de la epilepsia como minoritarios.
Carretón Ballester, María Carmen
core   +4 more sources

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Perfil demográfico y social de la epilepsia en una población vulnerable y de bajos recursos económicos en Bogotá, Colombia

Neurología, 2016
Resumen: Introducción: Existen pocos estudios que demuestren el perfil demografico y social de la epilepsia en poblaciones vulnerables y de bajos recursos económicos.
C.A. Espinosa Jovel, C.M. Pardo, C.M. Moreno, J. Vergara, D. Hedmont, F.E. Sobrino Mejía   +5 more
doaj   +1 more source

Efficacy and safety of eslicarbazepine acetate monotherapy in patients converting from carbamazepine. [PDF]

, 2018
OBJECTIVE: To evaluate the influence of prior use of carbamazepine (CBZ) and other antiepileptic drugs (AEDs) with a putatively similar mechanism of action (inhibition of voltage-gated sodium channels; VGSCs) on seizure outcomes and tolerability when ...
Abou-Khalil, Benbadis, Bonifacio, Chung, Commission on Classification and Terminology of the International League against Epilepsy (ILAE), Fisher, French, Hebeisen, Jacobson, Sperling, Sperling, Vazquez   +11 more
core   +2 more sources

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source