Results 71 to 80 of about 11,993 (190)

NEUROINFLAMACIÓN Y EPILEPSIA

TIP, 2016
RESUMENLa epilepsia es un trastorno neurológico que afecta a 50 millones de personas en el mundo. Se define por la presencia de crisis epilépticas espontáneas resultado de descargas sincrónicas de una población neuronal debido a un dinamismo anormal de las redes neuronales.
Omar Herrera-Vázquez, Andrea Toledo Rojas, Agnès Fleury   +2 more
openaire   +2 more sources

Respuesta clínica a brivaracetam en dos casos de epilepsia de ausencia juvenil farmacorresistentes

Anales del Sistema Sanitario de Navarra
Si bien solo el 20% de las personas con epilepsias generalizadas idiopáticas son farmacorresistentes, dicho porcentaje resulta bastante problemático si se toma en cuenta los escasos fármacos aprobados para este tipo de epilepsia.
Abel Alejandro Sanabria Sanchinel, Byron Daniel Bol Marroquín   +1 more
doaj   +1 more source

Frequência escolar em indivíduos com paralisia cerebral no Brasil

Developmental Medicine &Child Neurology, EarlyView.
Objetivo Identificar fatores associados à frequência escolar entre crianças, adolescentes e jovens adultos brasileiros com paralisia cerebral (PC), utilizando dados populacionais do Registro Brasileiro de Paralisia Cerebral (RBPC). Método Este estudo transversal analisou dados de 774 indivíduos com PC, com idades entre 4 e 21 anos, registrados no RPBC.
Ricardo Rodrigues de Sousa Junior, Luana Cristina da Silva, Ana Cristina Resende Camargos, Eliane Beatriz Cunha Policiano, Lívia Ferreira Coutinho Alonso, Nadia Badawi, Israt Jahan, Gulam Khandaker, Maria De Las Mercedes Ruiz Brunner, Paula Silva de Carvalho Chagas, Hércules Ribeiro Leite   +10 more
wiley   +1 more source

Revisión en base a un caso sobre el uso y potencial de la estereoelectroencefalografía

Revista Médica Clínica Las Condes
Resumen: La epilepsia focal refractaria es un cuadro frecuente y de difícil manejo a nivel mundial. Cuando los estudios no invasivos no bastan para esclarecer el origen de las crisis, es necesario recurrir a estudios invasivos.
José Ignacio Otayza, MD, Andrés Horlacher, MD, Francesca Solari, MD   +2 more
doaj   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

Developmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa, Kirsi Mikkonen, Marjo Metsäranta, Sanna Toiviainen‐Salo, Sampsa Vanhatalo, Leena Lauronen, Päivi Nevalainen   +6 more
wiley   +1 more source

The Erasmus—Polyneuropathy Symptom Score for the Screening of Chronic Axonal Polyneuropathy: A Validation Study

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims Chronic axonal polyneuropathy is a common disorder that often remains undiagnosed. Early detection may enhance treatment of underlying risk factors and prevent long‐term complications. The Erasmus‐Polyneuropathy symptom score (E‐PSS) is a simple and rapid screening tool, consisting of six questions (score ranges 0–14). This
Noor E. Taams, Merel Huijg, Frederique H. Vermeij, Krista Kuitwaard, Rens Hanewinckel, Janet de Beukelaar, Evan L. Reynolds, Brian C. Callaghan, M. Arfan Ikram, Pieter A. van Doorn   +9 more
wiley   +1 more source

Smartphone videos for infantile epileptic spasms triaging and assessment (VISTA study): Impact of education and standardized clinical history on diagnostic accuracy

Epilepsia Open, Volume 11, Issue 4, Page 1301-1313, August 2026.
Abstract Objective Diagnostic and treatment delays in infantile epileptic spasms syndrome (IESS) increase the risk of poor neurodevelopmental outcomes. Early clinical recognition of IESS is essential, especially in regions lacking expedited access to electroencephalograms (EEG).
Christine L. Shrock, Margaret C. Savage, Lauren Sham, Christopher Cortina, Kathryn P. Gray, I‐Hsiu Lee, Chahnez C. Triki, Jacqueline French, J. Helen Cross, Orrin Devinsky, Jo M. Wilmshurst, Archana A. Patel   +11 more
wiley   +1 more source

A first in disease trial of the safety, tolerability, and anti‐seizure effects of ES‐481 in drug‐resistant epilepsy

Epilepsia Open, Volume 11, Issue 4, Page 1329-1342, August 2026.
Abstract Objectives ES‐481 is a novel potent and selective antagonist of TARP‐y8‐dependent AMPA receptors. We aimed to assess the potential efficacy, safety and tolerability, and pharmacokinetics of different doses of ES‐481 as an add‐on anti‐seizure medication (ASM) in adults with drug‐resistant epilepsy (DRE). Methods This was a Phase 2A double‐blind,
Emma C. Foster, Lyn Millist, Jack Germaine, Stephanie Chamorro, Caitlin Roberts, John‐Paul Nicolo, Sean Hosking, Piero Perucca, Saul Mullen, Heather Robinson, Rebecca Wharrie, Brittany Walsh, David Reutens, Kimberley Irwin, Hao Zeng, Robert Niecestro, Terence J. O'Brien   +16 more
wiley   +1 more source

Tratamiento urgente de las crisis epilépticas

Kranion
Introducción: El estado epiléptico es una urgencia médica que exige una intervención terapéutica inmediata para evitar daño neurológico y reducir la mortalidad.
Dulce M.ª Campos-Blanco, Elena Varas-Martín   +1 more
doaj   +1 more source

Characteristics and long‐term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population‐based study

Epilepsia Open, Volume 11, Issue 4, Page 1314-1328, August 2026.
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng, Päivi Koroknay‐Pál, Henri Lehtinen, Eija Gaily, Atte Karppinen, Anders Paetau, Olli Tynninen, Heta Leinonen, Aki Laakso, Eeva‐Liisa Metsähonkala   +9 more
wiley   +1 more source