Results 211 to 220 of about 18,565 (309)

Predictors of etiology and drug resistance in children with new-onset focal seizures. [PDF]

Epilepsia Open
Lee BC, Dale RC, Barnes EH, Mohammad SS, Gupta S, Wong C, Gill D, Kothur K.   +7 more
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Cannabinoid Therapies in Less-Common Disorders: Clinical Evidence and Formulation Strategies. [PDF]

Diseases
Afonso S, Gonçalves J, Brinca AT, Rosendo LM, Rosado T, Duarte AP, Gallardo E.   +6 more
europepmc   +1 more source

Learning with Patient Campaigners About a German Drug Scandal

Berichte zur Wissenschaftsgeschichte, EarlyView.
The West German drug Duogynon was internationally marketed as a “hormone pregnancy test” (HPT) between the 1950s and 1980s. In the late 1960s it came under suspicion for inducing miscarriage, spina bifida, and a spectrum of birth defects similar to those caused by the sedative thalidomide.
Jesse Olszynko‐Gryn, Anja Suter, Edmund Bolger, Birgit Nemec   +3 more
wiley   +1 more source

Taking It to the Limit: A Novel GRIN2D Developmental and Epileptic Encephalopathy Rodent Model With Severe Seizures. [PDF]

Epilepsy Curr
Eyal S.
europepmc   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source

Efficacy and safety of cannabidiol in a single-center pediatric drug-resistant epilepsy cohort: a retrospective study. [PDF]

Front Neurol
Butera A, Spoto G, Ceraolo G, Grella M, Giunta I, Albertini ML, Consoli C, Sferro C, Spanò M, Di Rosa G, Nicotera AG.   +10 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Adjunctive acetazolamide for drug-resistant seizures in SLC6A1-related neurodevelopmental disorder: An exploratory case series. [PDF]

Epilepsia Open
Melikishvili G, Dulac O, Koniashvili O, Mamardashvili G, Gachechiladze T, Tabatadze N, Melikishvili M, Gamirova R, Tomenko T, Bakhtin I, Freed A, Bossi E, Ben-Zeev B, Kluger G, Falace A, Riva A, Kaila K, Striano P.   +17 more
europepmc   +1 more source