Results 1 to 10 of about 945,871 (357)

Clinical Factors Related to Outcomes in Pediatric Epilepsy Surgery: Insight into Predictors of Poor Surgical Outcome

Neurologia Medico-Chirurgica, 2023
Successful surgery for drug-resistant pediatric epilepsy can facilitate motor and cognitive development and improve quality of life by resolution or reduction of epileptic seizures.
Satoru OSHINO, Naoki TANI, Hui KHOO, Kuriko KAGITANI-SHIMONO, Shin NABATAME, Koji TOMINAGA, Takufumi YANAGISAWA, Masayuki HIRATA, Haruhiko KISHIMA   +8 more
doaj   +1 more source

Periictal water drinking revisited: Occurrence and lateralizing value in surgically confirmed patients with focal epilepsy

Epilepsia Open, 2023
Objective Periictal water drinking (PIWD), which is a rare seizure‐related autonomic behavior, has been reported in temporal lobe epilepsy (TLE) but only rarely in extra‐TLE. Additionally, the lateralizing value of PIWD is controversial.
Yuhei Tanno, Takashi Matsudaira, Naotaka Usui, Hiroshi Ogawa, Kentaro Tokumoto, Norihiko Kawaguchi, Akihiko Kondo, Takuji Nishida, Yukitoshi Takahashi   +8 more
doaj   +1 more source

Integration of interictal EEG source localization in presurgical epilepsy evaluation – A single‐center prospective study

Epilepsia Open, 2023
Objective To investigate cost in working hours for initial integration of interictal EEG source localization (ESL) into clinical practice of a tertiary epilepsy center, and to examine concordance of results obtained with three different ESL pipelines ...
Gadi Miron, Thomas Baag, Kara Götz, Martin Holtkamp, Bernd J. Vorderwülbecke   +4 more
doaj   +1 more source

Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons [PDF]

, 2020
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is ...
Jansen, Laura A, Joshi, Suchitra, Kapur, Jaideep, Roden, William H   +3 more
core   +2 more sources

Effectiveness and tolerability of perampanel monotherapy in children with newly diagnosed focal epilepsy

Frontiers in Neurology, 2023
ObjectiveTo examine the clinical effectiveness and tolerability of perampanel (PER) as initial monotherapy in pediatric patients with newly diagnosed focal epilepsy.MethodsA retrospective analysis was conducted on 62 children with newly diagnosed focal ...
Fen Zhao, Fen Zhao, Ying Ren, Ying Ren, Guifu Geng, Guifu Geng, Tong Zhang, Tong Zhang, Wandong Hu, Wandong Hu, Huan Zhang, Huan Zhang, Ruifeng Jin, Ruifeng Jin, Jianguo Shi, Jianguo Shi, Zaifen Gao, Zaifen Gao, Hongwei Zhang, Hongwei Zhang, Yong Liu, Yong Liu   +21 more
doaj   +1 more source

The National Comprehensive Governance for epilepsy prevention and control in China

Epilepsia Open, 2022
This article describes “the national comprehensive governance for epilepsy prevention and control in China” as an example of a strategic working program for the prevention and control of epilepsy at a national level. The comprehensive governance includes
Shichuo Li, Yuping Wang, Wenzhi Wang, Dong Zhou, Hui Zhang, Lirong Duan, Ding Ding, Yuwu Jiang, Yi Wang, Xiaoyan Liu, Zhen Hong   +10 more
doaj   +1 more source

The role of the ketogenic diet in patients with epilepsy. A brief literary review and a clinical example

Русский журнал детской неврологии, 2023
Despite the advances in pharmacology, there are still some patients with drug-resistant inoperable epilepsy. Individual ketogenic diet might be an effective measure to prevent seizures.
M. Yu. Bobylova, E. I. Novyachkova, K. S. Romanovskaya, L. N. Mukhina, K. Yu. Mukhin   +4 more
doaj   +1 more source

Bilateral asymmetric tonic seizure in insulo-opercular epilepsy: an anatomo-electro-clinical study

Acta Epileptologica, 2020
Background Insulo-opercular seizures are highly heterogeneous in seizure semiology and electrical features. Bilateral asymmetric limb posturing, as a classical pattern of supplementary sensorimotor area (SMA) seizure, also occurs in insulo-opercular ...
Xiangshu Hu, Kaihui Li, Xiao Wang, Ping Yang, Qinghua Tan, Danfang Li, Xiaobo Wang, Fang Zeng, Yang Jin, Lingxia Fei, Hua Li, Junxi Chen, Qiang Guo   +12 more
doaj   +1 more source

Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency) [PDF]

, 2010
Pyridoxine-dependent epilepsy was recently shown to be due to mutations in the ALDH7A1 gene, which encodes antiquitin, an enzyme that catalyses the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-{alpha}-aminoadipic semialdehyde/L-{Delta}
Adam, Basura, Baxter, Bennett, Bernhard Schmitt, Cheryl Hemingway, Clayton, Clayton, Cornelis Jakobs, Eduard A. Struys, Emma J. Footitt, Ernst Christensen, François Feillet, Gallagher, Gospe, Goto, Hoffmann, Hunt, Janet Rennie, Kaczorowska, Kanno, Karin Tuschl, Kevin A. Mills, Kim, Kluger, Kurlemann, Lauras, M. Imelda Hughes, Mike G. Pike, Mills, Nabbout, Neil Marlow, Olivier Dulac, Ormazabal, Pascale De Lonlay, Peduto, Perozich, Peter Baxter, Peter T. Clayton, Philippa B. Mills, Plecko, Plecko, Rankin, Rima Nabbout, Salomons, Sameer M. Zuberi, Sarah Aylett, Sophia Varadkar, Striano, Tang, William J. Craigen   +50 more
core   +20 more sources

Impact of COVID‐19 pandemic on epilepsy care in Japan: A national‐level multicenter retrospective cohort study

Epilepsia Open, 2022
Objective The impact of the coronavirus disease 2019 (COVID‐19) pandemic on epilepsy care across Japan was investigated by conducting a multicenter retrospective cohort study.
Naoto Kuroda, Takafumi Kubota, Toru Horinouchi, Naoki Ikegaya, Yu Kitazawa, Satoshi Kodama, Izumi Kuramochi, Teppei Matsubara, Naoto Nagino, Shuichiro Neshige, Temma Soga, Yutaro Takayama, Daichi Sone, IMPACT‐J EPILEPSY (In‐depth Multicenter analysis during Pandemic of Covid‐19 Throughout Japan for EPILEPSY practice) study group   +13 more
doaj   +1 more source