ABSTRACT Objective Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer’s disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD ...
Xuerui Pang +8 more
wiley +1 more source
Resolution of generalized tonic seizures following focal ablative or resective surgery. [PDF]
Kampman SL +3 more
europepmc +1 more source
Abstract Background Differences in Frontal Alpha Asymmetry (FAA), derived from the electroencephalogram (EEG), have been associated with approach‐withdrawal behavior, although inconsistently. The current study examined how early patterns of FAA during the first 2 years of life relate to various socioemotional characteristics (at 2 years) and ultimately
Viviane Valdes +3 more
wiley +1 more source
Bilateral ictal eye closure in focal epileptic seizures: SEEG retrospective observational assessment from a tertiary epilepsy center. [PDF]
Vassallo P +10 more
europepmc +1 more source
Central Nervous System Tumors in Xeroderma Pigmentosum: Five Cases and Review of the Literature
Abstract Background Xeroderma pigmentosum (XP) is a rare autosomal recessive DNA‐repair disorder characterized by extreme ultraviolet radiation (UVR) sensitivity, markedly increased cutaneous malignancy risk, and progressive neurological disease in approximately one‐third of patients.
Farrah S. Bakr +4 more
wiley +1 more source
New-Onset Complex Partial Seizures Progressing to Intractable Epilepsy in a Young Female With Bifrontal Encephalomalacia and a Remote History of Traumatic Brain Injury. [PDF]
Villegas KJ +4 more
europepmc +1 more source
Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer +15 more
wiley +1 more source
Microstructure imaging in patients undergoing evaluation for epilepsy surgery or low-grade glioma: Clinical utility of a novel diffusion MRI method. [PDF]
Grubor I +5 more
europepmc +1 more source
A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson +43 more
wiley +1 more source
Long-Term Outcomes and Safety of Surgical Treatment Following Intracranial Electroencephalography Monitoring in Pediatric Epilepsy: A Single-Center Study. [PDF]
Shimogawa T +9 more
europepmc +1 more source

