Results 171 to 180 of about 29,221 (266)

A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia

Movement Disorders, EarlyView.
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson, Isaac Adanyeguh, David J. Arpin, Tetsuo Ashizawa, Benjamin Bender, Fernando Cendes, Xi Chen, Giulia Coarelli, Léo Coutinho, Andreas Deistung, Imis Dogan, Alexandra Durr, Jennifer Faber, for the ESMI MR Study Group, Juan Fernandez‐Ruiz, Mónica Ferreira, Marcondes C. França, Sophia L. Göricke, Shuo Han, Thomas Klockgether, Chen Liu, Jun Luo, Alberto R.M. Martinez, Sergio E. Ono, Chiadi U. Onyike, Gülin Öz, for the EUROSCA MR Study Group, Henry Paulson, Jerry L. Prince, Kathrin Reetz, Thiago J.R. Rezende, Matthis Synofzik, Hélio A. Ghizoni Teive, Sophia I. Thomopoulos, Paul M. Thompson, Dagmar Timmann, David Vaillancourt, Bart van de Warrenburg, Judith van Gaalen, Xingang Wang, Philipp Wegner, Sarah H. Ying, Ian H. Harding, Carlos R. Hernandez‐Castillo   +43 more
wiley   +1 more source

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study. [PDF]

Epilepsia
Feng X, Chari A, Eriksson MH, Prentice F, He X, Xie H, Sepeta L, Tahir MZ, Clayden JD, Tisdall MM, Baldeweg T, Piper RJ.   +11 more
europepmc   +1 more source

Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases

Movement Disorders, EarlyView.
Abstract Background Despite widespread cortical involvement in Lewy body diseases, conventional gray matter magnetic resonance imaging (MRI) shows limited sensitivity. Diffusion‐weighted MRI‐derived microstructural measures have shown utility in Alzheimer's disease, but their application across the Lewy body disease spectrum remains limited ...
Angeliki Zarkali, Ivelina Dobreva, Naomi Hannaway, Rohan Bhome, George E.C. Thomas, Steffani Carrera, Amanda J. Heslegrave, Elena Veleva, Henrik Zetterberg, Rimona S. Weil   +9 more
wiley   +1 more source

Commonalities and distinctions of static and dynamic functional connectivity density between left and right temporal lobe epilepsy. [PDF]

Sci Rep
Song C, Zhang X, Cheng J, Ma K, Lian Y, Zhang Y.   +5 more
europepmc   +1 more source

Spatiotemporal Progression Patterns of Striatal Dopamine Depletion and Cerebral Hypoperfusion in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background The identification of Parkinson's disease (PD) subtypes is crucial for predicting the disease course and designing personalized therapeutic strategies. Objectives The aim of the study was to characterize the heterogeneity of the spatiotemporal evolutionary patterns of striatal dopamine depletion and cerebral hypoperfusion in PD ...
Yeeun Sun, Youngseok Choi, Chan Wook Park, Han Kyu Na, Hye Sun Lee, Yun Joong Kim, Young H. Sohn, Phil Hyu Lee, Jeyeon Lee, Seok Jong Chung   +9 more
wiley   +1 more source

Atlas of Brain Glucose Metabolism Using Deuterium Metabolic Imaging at 3 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Deuterium metabolic imaging (DMI) offers noninvasive magnetic resonance imaging (MRI)–based assessment of metabolism in vivo, making it a relevant paraclinical tool for diseases with neurological metabolic alterations. This study aimed to establish a normative reference atlas of brain glucose metabolism accounting for age and sex ...
Kamilla K. Trosborg, Nichlas V. Christensen, Malene Aastrup, Nikolaj Bøgh, Janne K. Mortensen, Hanne Gottrup, Per Borghammer, Mattias H. Kristensen, Esben S. S. Hansen, Sofie H. Christensen, Jack J. Miller, Rolf F. Schulte, Michael Vaeggemose, Lotte B. Bertelsen, Christoffer Laustsen   +14 more
wiley   +1 more source

Neuroanatomical correlates of neuropsychological dysfunction in pediatric pharmacoresistant epilepsy due to focal cortical dysplasia type II. [PDF]

Epilepsia Open
Arenivas A, Morris S, Lapin B, Li Y, Ferguson L, Jones SE, Blümcke I, Najm I, Busch RM, Wang ZI.   +9 more
europepmc   +1 more source

Depletion of microglial compensation in glial network: Disease‐associated response dynamics in the revised amyloid hypothesis

Neuroprotection, EarlyView.
The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei, Zixuan Huang, Wen Wang, Yan Meng   +3 more
wiley   +1 more source

Hippocampal Long Axis Differentiation in Memory and Seizure Networks. [PDF]

Epilepsy Curr
McClain K, Nguyen QA, Sepeta L, Soltesz I, Liu A.   +4 more
europepmc   +1 more source

Epidemiological distribution of MRI‐based presumptive imaging diagnoses in a large general population of cats with suspected epileptic seizures

Veterinary Record, EarlyView.
Abstract Background The reported prevalence of feline idiopathic epilepsy (IE) and presumptive imaging diagnoses based on magnetic resonance imaging (MRI) varies depending on factors such as differences between primary care versus referral study populations.
Anna Knebel, Sebastian Meller, Julien Labruyère, Holger A. Volk   +3 more
wiley   +1 more source