Utility of repeat stereotactic EEG in pediatric patients with tuberous sclerosis
Abstract Objective Tuberous sclerosis complex (TSC) is a rare genetic disorder associated with early‐onset drug‐resistant epilepsy (DRE) secondary to intracranial tubers. Many patients undergo stereo‐EEG (sEEG) for seizure onset localization, sometimes requiring multiple sEEGs and subsequent epilepsy surgeries. Our objective was to evaluate the effects
Julie Uchitel +14 more
wiley +1 more source
Application value of resting-state fMRI in preoperative lateralization of language areas in epilepsy with left-sided epileptogenic foci. [PDF]
Wang Z +6 more
europepmc +1 more source
Abstract Objective Epileptic spasms (ES) in children carry a high risk of neurodevelopmental delay, yet predictors of long‐term surgical outcome remain incompletely defined. This study aimed to evaluate seizure outcomes following epilepsy surgery and to identify independent prognostic factors for postoperative recurrence.
Hua Li +7 more
wiley +1 more source
Case Report: Early surgical intervention for epilepsy with mild MOGHE: timing and clinical efficacy. [PDF]
Sun Y +11 more
europepmc +1 more source
Transcriptional signatures of cortical morphometric variability in temporal lobe epilepsy
Abstract Objective Widespread cognitive deficits in temporal lobe epilepsy (TLE) are associated with macroscale brain structural changes. However, the correlation between the changes in the cortical morphological similarity of the TLE and gene expression remains unclear.
Yaping Dong +5 more
wiley +1 more source
Initial negative imaging in GATOR1-associated genetic epilepsy does not preclude the existence of a focal, resectable epileptogenic zone: illustrative cases. [PDF]
Ruan Y +10 more
europepmc +1 more source
The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia +4 more
wiley +1 more source
Autonomic Network Signatures of Interictal Cardiorespiratory Dysfunction in Patients With Temporal Lobe Epilepsy. [PDF]
Pourmotabbed H +6 more
europepmc +1 more source
Abstract Objective Self‐limited epilepsy with centrotemporal spikes (SeLECTS), although characterized by well‐controlled seizures, is frequently associated with persistent cognitive deficits in affected children. This study aimed to investigate whether hub dysfunction of the salience network (SN) is associated with cognitive impairment in SeLECTS ...
Chen Yang +9 more
wiley +1 more source

