Results 31 to 40 of about 22,438 (261)

Antiepileptic activity of four selected Skullcap (Scutellaria) species on mice

open access: yesVan Tıp Dergisi, 2018
INTRODUCTION: Epilepsy is a common neurological disorder which has different types. Epileptic convulsions are decreasing life quality of patients and can even cause death. Medical treatment of epilepsy includes drugs and surgical interventions.
Okan Arıhan   +3 more
doaj   +1 more source

Dynamic Transitions of Epilepsy Waveforms Induced by Astrocyte Dysfunction and Electrical Stimulation

open access: yesNeural Plasticity, 2020
Experimental studies have shown that astrocytes participate in epilepsy through inducing the release of glutamate. Meanwhile, considering the disinhibition circuit among inhibitory neuronal populations with different time scales and the feedforward ...
Honghui Zhang   +5 more
doaj   +1 more source

Study about cognitive performances in elderly patients with epilepsy [PDF]

open access: yesRomanian Journal of Neurology, 2010
A significant proportion of patients with epilepsy are at an increased risk of cognitive impairment. The goal of our study was to assess the cognitive state in elderly patients with idiopathic epilepsy.
Denisa Pirscoveanu   +5 more
doaj   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier   +6 more
wiley   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Comparison of Alexithymia among Patients with Tonic-Clonic Epilepsy, Juvenile Myoclonic Epilepsy and Healthy Individuals

open access: yesJournal of Ardabil University of Medical Sciences, 2017
Background & objectives: Epilepsy is a chronic neurological disorder that disrupts normal brain activity due to abnormal electrical discharge of brain cells. Mood swings, depression and anxiety are the common complications in epilepsy.
Zarife Sohrabi   +4 more
doaj  

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou   +6 more
wiley   +1 more source

Pitfalls in the diagnosis of new-onset frontal lobe seizures

open access: yesEpilepsy and Behavior Case Reports, 2014
We reported the case of a young woman who received an antiepileptic drug after a first possible generalized tonic-clonic seizure with no clear inter-ictal epileptic paroxysms in the routine electroencephalogram.
S. Bourion-Bédès   +7 more
doaj   +1 more source

Comorbid seizure reduction after pallidothalamic tractotomy for movement disorders: Revival of Jinnai’s Forel‐H‐tomy

open access: yesEpilepsia Open, 2021
Forel‐H‐tomy for intractable epilepsy was introduced by Dennosuke Jinnai in the 1960s. Recently, Forel‐H‐tomy was renamed to “pallidothalamic tractotomy” and revived for the treatment of Parkinson's disease and dystonia. Two of our patients with movement
Shiro Horisawa   +5 more
doaj   +1 more source

The research of the generalized tonic-clonic seizure epilepsy by resting state Fmri [PDF]

open access: yesAdvances in Intelligent Systems Research, 2015
In this study, we investigated the human brain functional network of patients with generalized tonic and clonic seizure (GTCS) epilepsy by using the resting-state functional magnetic resonance imaging (fMRI) and complex network theory. Adjacency matrices of the networks of GTCS group and normal control group were constructed by the method of Pearson ...
Xiaoping Yang   +3 more
openaire   +1 more source

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