Results 51 to 60 of about 22,438 (261)

The hidden burden of sleep in adolescents with idiopathic generalized epilepsy

Epileptic Disorders, EarlyView.
Abstract Background Idiopathic Generalized Epilepsies (IGEs) are electroclinical syndromes characterized by distinct seizure types, EEG patterns, and presumed polygenic inheritance. While seizure prognosis is often favorable, sleep disturbances, behavioral and emotional difficulties, and executive function impairment are common, especially during ...
Carlo Alberto Quaranta, Martina Paola Zanaboni, Elena Ripamonti, Gaia Garghetti, Massimiliano Celario, Serena Grumi, Helene Vitali, Valentina De Giorgis, Ludovica Pasca   +8 more
wiley   +1 more source

Long-term outcomes of generalized tonic-clonic seizures in a childhood absence epilepsy trial [PDF]

Neurology, 2015
To determine incidence and early predictors of generalized tonic-clonic seizures (GTCs) in children with childhood absence epilepsy (CAE).Occurrence of GTCs was determined in 446 children with CAE who participated in a randomized clinical trial comparing ethosuximide, lamotrigine, and valproate as initial therapy for CAE.As of June 2014, the cohort had
Shlomo Shinnar, Avital Cnaan, Fengming Hu, Peggy Clark, Dennis Dlugos, Deborah G. Hirtz, David Masur, Eli M. Mizrahi, Solomon L. Moshé, Tracy A. Glauser, Harry Abram, Ellen Albers, Samar J. Bahna, Karen Ballaban-Gil, Jose Barrera, Tekolla Belaineh, Mary Bertrand, Hal Blumenfeld, Sarah Borror, Charlie Borzy, Susan Brantz, Candace Cardoza, Kevin Chapman, Harry T. Chugani, Robert R. Clancy, Peggy O. Clark, Yong Collins, Terrie Conklin, Joan A. Conry, Patricia K. Crumrine, Jason Czachor, M. Susan Dean, Sandra Dewar, Michael Duchowny, Deborah Dye, Tammy Eaton, Mary Jo Elgie, Michelle Ellis, Roy Elterman, Daniella Escobedo, Andrew Francis, L. Matthew Frank, Tracy A. Glauser, Hilary Gray, La June Grayson, May L. Griebel, Laurie Guidry, Samantha Hagopian, Jennifer Haky, Amelia Halac, Angel Hernandez, Lee Howard, Krisa Hoyle Elgin, Pong Kankirawatana, Kent R. Kelley, Juli Kidd, Divya Khurana, Paul M. Levisohn, Donna Lowery, Ricardo Luzondo, Mary Lou Maher, Angela Martinez, Karen McEwen, Sarah J. McVey, Mary Miceli, Daniel K. Miles, Jennifer Monahan, Elena Morales, Dianne Morus, Cyndi Mott, JoAnn Narus, Mark Nespeca, Edward Novotny, Suzanne Oken, Juliann Paolicchi, Bryan Philbrook, Tami Quintero, Amber Reese-Porter, Jong M. Rho, Tracee Ridley-Pryor, Angela Riggs, Colin Roberts, Kathy Romine, Veronique Ruppe, Russell P. Saneto, Raman Sankar, Mark S. Scher, Rebecca Schultz, Michael Schwabe, Dina Schwam, Sagar Shah, Gregory Sharp, Rolla Shbarou, Ruth C. Shinnar, Shlomo Shinnar, Marcio Sotero de Menezes, Donovan Stock, Christina Lopez Talley, Susanna Taylor, Mamello Tekateka, Doris A. Trauner, Edwin Trevathan, William R. Turk, Colin B. Van Orman, GeorgAnn Vanderjagt, Mary Warde, Jorge Vidaurre, Arie Weinstock, Nanastasia Welnick, Rhonda Werner, James Wheless, Angus A. Wilfong, Korwyn Willliams, Shelley Williams, Teresa Williams, Jennifer Williamson, Khaled Zamel, Mary Zupanc, Peter C. Adamson, Brian K. Alldredge, Tina Alvarado-Taylor, Anne Berg, Gordon Bernhard, Blaise Bourgeois, Brooke Bintliff-Janisak, Jeffrey Blumer, Jeffrey R. Buchhalter, Edmund V. Capparelli, Joan A. Conry, Jeanine Dahlquist, Kaitlyn Daniels, Mignon Davis, Julie DiStefano-Pappas, Michael Donaghue, Eileen Dorsey, Nakeshia Drummond, Shonda Evans, Brandy E. Fureman, Peter R. Gilbert, Melanie Gleave, Gregory A. Grabowski, Rong Guo, Gregory Grabowski, Melissa Grubb, Marla J. Hamberger, Dale Hesdorffer, Emily Hirschfeld, Michael Hoffman, Paula Jackson, Margaret Jacobs, Mehdi Keddache, Sudha K. Kessler, Michael Kuhlmann, Denise LaGory, Laura Lawrence, Paul M. Levisohn, David Loring, Xianqun Luan, Chunyan Liu, Jonathan Masur, Susan McMahan, Katherine Montefiore, Guriya Nandwani, John Nevy, Virginia Nissen, Valerie O’Brien, Philip Overby, Nicholas Peccina, John M. Pellock, John P. Pestian, Michael D. Reed, John H. Rodman, Ellen B. Roecker, Julie Schneider, Charles Scott, Mayadah Shabbout, David Shera, Ruth C. Shinnar, Sarah Srodulski, Gerri Tangren, Marc Taylor, Nirmala Thevathasan, Tonia Toon, Maria Vasconcelos, Alexander A. Vinks, Gretchen Von Allmen, Clare Weiler, Erica F. Weiss, Sheila Wolfer   +188 more
openaire   +2 more sources

Anticonvulsant effects of pentoxifylline on seizures induced by pentylenetetrazole and maximal electroshock in male mice: The role of the nitrergic pathway

IBRO Neuroscience Reports
Introduction: Epilepsy remains a challenge, with one-third of patients experiencing refractory seizures despite current anti-seizure medications. The nitrergic system, which involves nitric oxide (NO) and NO synthase (NOS) enzymes, plays a complex role ...
Mohammad Keshavarzi, Moein Ghasemi, Mohammad Amin Manavi, Ahmad Reza Dehpour, Hamed Shafaroodi   +4 more
doaj   +1 more source

Sudden unexpected death in epilepsy in a 14-year-old girl: case report and literature review

Journal of International Medical Research, 2018
Background Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in people with epilepsy. The pathogenesis of SUDEP is still unclear.
Xinyue Zhang, Lichao Sun, Li Cui, Weihong Lin   +3 more
doaj   +1 more source

Prevalence of childhood and adolescence epilepsy in Upper Egypt (desert areas)

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018
Background A high prevalence of epilepsy in children is frequently found in developing countries. Objective This study aimed to determine the prevalence and clinical pattern of childhood and adolescence epilepsy in Upper Egypt.
Wafaa M. Farghaly, Mohamed A. Abd Elhamed, Enas M. Hassan, Wael T. Soliman, Mohamed A. Yhia, Nermin A. Hamdy   +5 more
doaj   +1 more source

Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic–clonic seizures

The Journal of Physiology, 2005
Mutations in SCN1A, the gene encoding the brain voltage‐gated sodium channel α1 subunit (NaV1.1), are associated with genetic forms of epilepsy, including generalized epilepsy with febrile seizures plus (GEFS+ type 2), severe myoclonic epilepsy of infancy (SMEI) and related conditions.
Thomas H, Rhodes, Carlos G, Vanoye, Iori, Ohmori, Ikuo, Ogiwara, Kazuhiro, Yamakawa, Alfred L, George   +5 more
openaire   +3 more sources

Systematic literature review of the humanistic and economic burden of focal epilepsy and primary generalized tonic–clonic seizures in adults

Epilepsia Open
This systematic literature review (SLR) assessed the humanistic and economic burden of focal epilepsy and primary generalized tonic–clonic seizures (PGTCS) in adults to evaluate these domains in both populations and identify evidence gaps to inform ...
Simona Boccaletti, Eleanor Lucas, Annabel Nixon, Nikolina Boskovic, Giorgio Di Dato   +4 more
doaj   +1 more source

A clinical and pathological study in patients with sudden unexpected death in Epilepsy

Acta Epileptologica, 2019
Background Sudden unexpected death of epilepsy (SUDEP) is a severe outcome of epilepsy. This study aimed to report the clinical and pathological findings in patients with SUDEP. Methods The record of patients with sudden death was screened.
Weihua Yu, Ying Zhu, Qingshu Li, Xin Tian, Peng Zhang, Yang Lü   +5 more
doaj   +1 more source

Exploring the efficacy and safety of perampanel in epilepsia partialis continua: A case series

Epileptic Disorders, EarlyView.
Abstract Background Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus (SE), which is commonly drug‐resistant requiring treatment with multiple antiseizure medications (ASM). There are no established guidelines for pharmacological management.
Setareh Lahsaee, Kristin M. Ikeda, Stephanie Woodroffe, Benjamin P. Whatley   +3 more
wiley   +1 more source

CLINICAL CASE OF PREGNANT PATIENT WITH TEMPORAL EPILEPSY AND MYOCLONIC EPILEPTIC SEIZURES

Эпилепсия и пароксизмальные состояния, 2016
Rationale: It is thought that temporal lobe epilepsy tends to show three types of seizures: simple partial seizures, complex partial seizures and secondary generalized motor (tonic ore tonic-clonic) seizures.
V. O. Generalov, T. R. Sadykov, N. I. Klimenchenko, A. M. Yugay, Yu. V. Kazakova, E. V. Tsalagova, O. V. Shetikova   +6 more
doaj