Results 121 to 130 of about 693,260 (339)

Efficiency of vagus nerve stimulation in epilepsy (literature review and case report)

open access: yesРусский журнал детской неврологии, 2019
Despite significant advances in epileptology, approximately one-third of patients suffer from drug-resistant epilepsy. Numerous approaches are currently available to treat epilepsy; however, there are still many patients with treatment-resistant epilepsy,
O. A. Pylaeva   +3 more
doaj   +1 more source

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol [PDF]

open access: yes, 2015
Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy.
A Bathen-Noethen   +94 more
core   +6 more sources

Three‐Component Synthesis of γ‐Amino Esters with α‐Quaternary Carbon Centers via NHC/Photoredox Dual Catalysis

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
γ‐Amino acid derivatives with an α‐quaternary center are prevalent in medicinally important compounds. A dual N‐heterocyclic carbene/photocatalytic pathway is developed for the three‐component synthesis of α, α ‐disubstituted γ‐amino esters. This methodology allows for the rapid synthesis of diverse libraries of γ‐amino esters in good yields.
Adam X. Wayment, Karl A. Scheidt
wiley   +1 more source

Cortical thickness and sulcal depth: insights on development and psychopathology in paediatric epilepsy. [PDF]

open access: yes, 2015
BackgroundThe relationship between cortical thickness (CThick) and sulcal depth (SDepth) changes across brain regions during development. Epilepsy youth have CThick and SDepth abnormalities and prevalent psychiatric disorders.AimsThis study compared the ...
Caplan, Rochelle   +3 more
core   +2 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

open access: yesAdvanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei   +15 more
wiley   +1 more source

Epilepsy and its Treatment [PDF]

open access: green, 1902
W. H. Broadbent
openalex   +1 more source

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