Results 141 to 150 of about 403,746 (315)

Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs [PDF]

open access: yes
Epilepsy is one of the most common chronic neurological conditions in the dog, estimated to affect 0.6 to 0.75 per cent of dogs. Owners of dogs with epilepsy have previously indicated that their dog's quality of life (QoL) is of greatest importance to ...
Packer, R M A, Volk, H A
core   +1 more source

Detection of temporal-lobe epilepsy with the physiological responses to fear and anxiety [PDF]

open access: yes, 2020
Epilepsy is a neurological disease caused by an abnormal neuronal activity on a region of the brain, which provokes seizures and the loss of consciousness to its patients. Epilepsy can be very disabling, since patients do not know when crisis or seizures
Perich Pallaruelo, Marta
core  

BOLD and perfusion changes during epileptic generalised spike wave activity [PDF]

open access: yes, 2008
It is unclear whether neurovascular coupling is maintained during epileptic discharges. Knowing this is important to allow appropriate inferences from functional imaging studies of epileptic activity. Recent blood oxygen level-dependent (BOLD) functional
Carmichael, D.W.   +5 more
core   +1 more source

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

open access: yesAdvanced Science, EarlyView.
Wenxiang Meng and colleagues delve into the molecular mechanisms underlying curcumin's modulation of RNA post‐transcriptional N (6)‐methyladenosine (m6A) modification. It is found that curcumin interacts with the Z1‐type protein tyrosine phosphatase receptor (PTPRZ1), maintaining its enzymatic activity and thus regulating the phosphorylation of the m6A‐
Ninan Zhang   +9 more
wiley   +1 more source

Multivariate white matter alterations are associated with epilepsy duration [PDF]

open access: yesarXiv, 2020
Previous studies investigating associations between white matter alterations and duration of temporal lobe epilepsy (TLE) have shown differing results, and were typically limited to univariate analyses of tracts in isolation. In this study we apply a multivariate measure (the Mahalanobis distance), to capture the distinct ways white matter may differ ...
arxiv  

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol [PDF]

open access: yes, 2015
Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy.
A Bathen-Noethen   +94 more
core   +6 more sources

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

open access: yesAdvanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei   +15 more
wiley   +1 more source

A CLINICAL CASE OF SYNGAP1 GENE MUTATION IN A GIRL WITH EPILEPSY, MENTAL RETARDATION, AUTISM, AND MOTOR DISORDERS

open access: yesРусский журнал детской неврологии, 2015
The introduction of the latest genetic techniques into practice could discover a basis for the comorbidity of genetic epilepsies and behavioral disturbances with cognitive impairments.
M. Yu. Bobylova   +7 more
doaj   +1 more source

Ontology and Knowledge Management System on Epilepsy and Epileptic Seizures [PDF]

open access: yesarXiv, 2010
A Knowledge Management System developed for supporting creation, capture, storage and dissemination of information about Epilepsy and Epileptic Seizures is presented. We present an Ontology on Epilepsy and a Web-based prototype that together create the KMS.
arxiv  

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