Results 171 to 180 of about 403,746 (315)

Cortical thickness and sulcal depth: insights on development and psychopathology in paediatric epilepsy. [PDF]

open access: yes, 2015
BackgroundThe relationship between cortical thickness (CThick) and sulcal depth (SDepth) changes across brain regions during development. Epilepsy youth have CThick and SDepth abnormalities and prevalent psychiatric disorders.AimsThis study compared the ...
Caplan, Rochelle   +3 more
core   +2 more sources

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

EPI-VALID : Validation of an algorithm for identifying patients with epilepsy in the SNDS using data from the CONSTANCES cohort [PDF]

open access: yesarXiv
Introduction: The HAS conducted a study in 2018 using the French National Health Data System (SNDS) on the care pathway of patients with epilepsy. This study used 2 algorithms to identify patients with epilepsy, based on hospitalization for epilepsy, insurance for chronic severe epilepsy, and antiepileptic drug (AE) dispensing, with exclusion of AEs ...
arxiv  

Immunostimulatory Hydrogel with Synergistic Blockage of Glutamine Metabolism and Chemodynamic Therapy for Postoperative Management of Glioblastoma

open access: yesAdvanced Science, EarlyView.
To address the challenge of postoperative recurrence, Combo Gel, a peptide‐based hydrogel that integrates glutamine metabolism modulation with chemodynamic therapy (CDT) is engineered. This innovative system, containing CB‐839 and copper peptide nanoparticles (Cu‐His NPs), enhances CDT's efficacy and promotes immunogenic cell death, thereby ...
Yiran Guo   +9 more
wiley   +1 more source

Advances in the pathogenesis of Rett syndrome using cell models

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 532-541, December 2022., 2022
Most Rett syndrome (RTT) patients are affected by the MECP2 gene mutations. And the mutations of MECP2 have wide effects on different cell types of nervous system, including neurons, astrocytes, oligodendrocytes and microglia, which always combined together to lead to abnormalities in the whole neural network.
Sijia Lu, Yongchang Chen, Zhengbo Wang
wiley   +1 more source

Digital Epidemiology: Leveraging Social Media for Insight into Epilepsy and Mental Health [PDF]

open access: yesarXiv
Social media platforms, particularly Reddit's r/Epilepsy community, offer a unique perspective into the experiences of individuals with epilepsy (PWE) and their caregivers. This study analyzes 57k posts and 533k comments to explore key themes across demographics such as age, gender, and relationships.
arxiv  

Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning‐Based Advanced Perspectives

open access: yesAdvanced Science, EarlyView.
Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim   +5 more
wiley   +1 more source

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