Results 311 to 320 of about 671,361 (363)

Development of Carborane‐Based Halogenated Naphthyridinone‐Analoga as Cannabinoid Receptor Type 2 (CB2R) Ligands

ChemMedChem, Accepted Article.
The cannabinoid receptor type 2 (CB2R) is overexpressed under pathological conditions. PET is a suitable non‐invasive imaging technique for diagnosing disease states, but requires a radiotracer that binds to CB2R with high affinity and selectivity. Currently, there is no suitable candidate routinely used in the clinics.
Lea Ueberham, Winnie Deuther-Conrad, Peter Lönnecke, Aleksandr Kazimir, Evamarie Hey-Hawkins   +4 more
wiley   +1 more source

Efficacy of Stiripentol Beyond Dravet Syndrome: A Retrospective Medical Record Review of Patients with Drug-Resistant Epilepsies. [PDF]

Neurol Ther
Soto-Insuga V, González-Alguacil E, Ballarà-Petitbò M, Lamagrande-Casanova N, Duat-Rodríguez A, Benítez-Provedo C, Cardenal-Muñoz E, García-Peñas JJ.   +7 more
europepmc   +1 more source

Chemometrics‐Assisted Electrochemical Device for Cannabidiol Detection in Real Cannabis sativa Samples

Chemistry–Methods, EarlyView.
GA: Four‐step process for cannabidiol (CBD) detection in Cannabis sativa extracts. (1) The plant extract is obtained. (2) An electrochemical sensor detects CBD using a screen‐printed electrode. (3) Electrochemical signatures of real samples are recorded, showing current vs. potential curves.
Wanda Cimmino, Ada Raucci, Antonella Miglione, Ciro Ascione, Ernesto Gargiulo, Nunzio Fiorentino, Serena Detti, Claudio D’Alfonso, Chiara Nieri, Sabino Napoletano, Antonietta Lombardozzi, Ibrahim A. Darwish, Giuseppina Chianese, Stefano Cinti   +13 more
wiley   +1 more source

Clinician and patient readiness to engage with community health workers at epilepsy care centers. [PDF]

Front Neurol
Chu FC, Jobst BC, Murray A, Dawson T, Frisard CF, Glidden B, Kaden SJ, Kiriakopoulos ET.   +7 more
europepmc   +1 more source

Deep Phenotyping of the Broader Autism Phenotype in Epilepsy: A Transdiagnostic Marker of Epilepsy and Autism Spectrum Disorder

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We conducted deep and minimal phenotyping of the broader autism phenotype (BAP) in people with epilepsy (PWE) and compared its expression with published rates in the general population and relatives of individuals with autism spectrum disorder (ASD‐relatives).
Annie E. Richard, Ingrid E. Scheffer, Sarah J. Wilson   +2 more
wiley   +1 more source

Sleep Deprivation Increases Mortality Risk Among Older Adults with Epilepsy. [PDF]

Healthcare (Basel)
Banerjee S, Khubchandani J, Nkemjika S.
europepmc   +1 more source

Salvage Trans‐Sylvian Peri‐Insular Hemispherotomy After Embolic Hemispherectomy

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Hemispherectomy and hemispherotomy represent well‐established treatments for drug‐resistant hemispheric epilepsy. An alternative endovascular procedure has been explored for cases with challenging surgical anatomy, which seeks to achieve the clinical effect of hemispherectomy via embolization of the major cerebral arteries and ...
Michael E. Baumgartner, Sudha Kessler, Kathleen Galligan, James E. Baumgartner, Benjamin C. Kennedy   +4 more
wiley   +1 more source

Psychiatric disorders with antiseizure medications in children: an analysis of the FDA adverse event reporting system database. [PDF]

Acta Epileptol
Gui J, Wang L, Meng L, Zhang X, Ma J, Jiang L.   +5 more
europepmc   +1 more source

Untargeted metabolomics reveals key metabolic alterations in pediatric epilepsy with insights into Tryptophan metabolism and the gut-brain axis. [PDF]

Sci Rep
Chojnowski K, Opiełka M, Urbanowicz K, Zawadzka M, Wangin K, Smoleński RT, Mazurkiewicz-Bełdzińska M.   +6 more
europepmc   +1 more source

Advancing FIRES Treatment: The Potential of Intrathecal Dexamethasone

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a rare, devastating epilepsy syndrome characterized by refractory status epilepticus following a febrile illness. Patient Description We describe a 12‐year‐old girl with FIRES who exhibited a remarkable clinical and electrographic response to intrathecal dexamethasone (IT‐DEX ...
Carol Park, Douglas R. Nordli III, Mohamed Taha, Henry David, Shawn Kacker, Tareq Kass‐Hout, Sonam Thind, Aurelie Hanin, Sana Said, Hiba A. Haider, Douglas R. Nordli Jr.   +10 more
wiley   +1 more source