Results 61 to 70 of about 609,740 (304)

Enhancing sudden unexpected death in epilepsy (SUDEP) research through development of common data elements

Epilepsia Open
Objective Sudden Unexpected Death in Epilepsy (SUDEP) is a fatal complication for individuals living with epilepsy and is associated with significant personal and public burden.
Sloka S. Iyengar, Elaine K. O'Loughlin, Lauren Harte‐Hargrove, Mary Holmay, Laura S. Lubbers, CURE Epilepsy SUDEP Data Standardization Project Steering Committee, CURE Epilepsy SUDEP Data Standardization Project Working Group Members   +6 more
doaj   +1 more source

Profile of once-daily zonisamide as monotherapy for treatment of partial seizures in adults. [PDF]

, 2013
Epilepsy is one of the most common neurologic disorders, affecting about 50 million people around the world. It is recognized that around 50% of patients with newly diagnosed epilepsy become seizure-free with the first drug treatment, so the choice of ...
Mula, M
core   +3 more sources

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Chinese expert consensus on disclosure of sudden unexpected death in epilepsy

Chinese Journal of Contemporary Neurology and Neurosurgery
Sudden unexpected death in epilepsy (SUDEP) refers to the sudden, unexpected, and witnessed or unwitnessed death of a patient with epilepsy, with or without evidence of a seizure, excluding status epilepticus, non-traumatic and non-drowning causes, and ...
Comorbidity Committee of China Association Against Epilepsy
doaj   +1 more source

Successful Hemispherotomy in a Patient with Encephalopathy with Continuous Spikes and Waves during Sleep Related to Neonatal Thalamic Hemorrhage: A Case Report with Intracranial Electroencephalogram Findings

Brain Sciences, 2021
Neonatal thalamic hemorrhage is a strong risk factor for developing encephalopathy with continuous spikes and waves during sleep (ECSWS), even when not accompanied by widespread cortical destruction.
Shimpei Baba, Tohru Okanishi, Toshiki Nozaki, Naoki Ichikawa, Kazuki Sakakura, Mitsuyo Nishimura, Takahiro Yonekawa, Hideo Enoki, Ayataka Fujimoto   +8 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

eIF5A and hypusination-related disorders: literature review and case report of DOHH-related encephalopathy

Journal of Neurodevelopmental Disorders
Background Eukaryotic initiation factor 5 A (eIF5A) and hypusination-related disorders (eIF5A-HRD) are recently described diseases caused by pathogenic heterozygous variants in the translation factor EIF5A or biallelic variants in the two enzymes ...
Álvaro Beltrán-Corbellini, Adrián Valls-Carbó, Rafael Toledano, Irene García-Morales, Irene Sánchez-Miranda Román, Antonio Gil-Nagel   +5 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Effect of fenfluramine on seizures and comorbidities in SCN8A‐developmental and epileptic encephalopathy: A case series

Epilepsia Open, 2022
SCN8A‐developmental and epileptic encephalopathy is caused by pathogenic variants in the SCN8A gene encoding the Nav1.6 sodium channel, and is characterized by intractable multivariate seizures and developmental regression.
Ángel Aledo‐Serrano, Borja Cabal‐Paz, Elena Gardella, Pablo Gómez‐Porro, Otilia Martínez‐Múgica, Alvaro Beltrán‐Corbellini, Rafael Toledano, Irene García‐Morales, Antonio Gil‐Nagel   +8 more
doaj   +1 more source

Screening for HLA-B*1502 Polymorphism in Febrile Seizure Predicted Lead to Epilepsy [PDF]

, 2009
Mutation in neuronal sodium channel -1-subunit gene (SCN1A) and neuronal sodium channel -1-subunit gene (SCN1B) has been linked with forms of generalized epilepsy with febrile seizure plus (GEFS+) and epileptic infantile syndrome like severe myoclonic ...
Bahtera, Tjipta, Faradz, Sultana MH, Jamal, Rahman A, Mian, Then Sue, Ratnaningrum, Safrina D   +4 more
core