Results 61 to 70 of about 384,910 (306)

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Relationship Between Hormones and Epilepsy

, 2018
The relationship between hormones and epilepsy is very complex. Hormones affect epilepsy, while epilepsy affects hormones. In addition, antiepileptic drugs have effects on seizures and hormones.
Kutlu, Gulnihal, Gülnihal KUTLU, Yasemin ÜNAL, Unal, Yasemin   +3 more
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP)

Epilepsia Open
Objective Sudden unexpected death in epilepsy (SUDEP) is a rare but devastating consequence of epilepsy and is the leading cause of death in people with epilepsy.
Sloka S. Iyengar, Elaine K. O'Loughlin, Lauren Harte‐Hargrove, Mary Holmay, Laura S. Lubbers, CURE Epilepsy SUDEP Data Standardization Project Steering Committee, Working Group Members   +6 more
doaj   +1 more source

Chinese expert consensus on disclosure of sudden unexpected death in epilepsy

Chinese Journal of Contemporary Neurology and Neurosurgery
Sudden unexpected death in epilepsy (SUDEP) refers to the sudden, unexpected, and witnessed or unwitnessed death of a patient with epilepsy, with or without evidence of a seizure, excluding status epilepticus, non-traumatic and non-drowning causes, and ...
Comorbidity Committee of China Association Against Epilepsy
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Epilepsy and Sport

, 2015
Epilepsy is a commonly encountered disorder in Turkey and throughout the world. It is widely believed that exercise enhances seizures, and that traumas and accidents occur more frequently in epileptic patients.
Emine TAŞKIRAN, Çiğdem ÖZKARA
core   +1 more source

Demonstration project on epilepsy in Brazil - Outcome assessment [PDF]

, 2007
Purpose: To assess the outcome of patients with epilepsy treated at primary care health units under the framework of the demonstration project on epilepsy in Brazil, part of the WHO/ILAE/IBE Global Campaign Against Epilepsy. Method.
Lucia H.N. Marques, Carlos A.M. Guerreiro, Javier Espíndola, Cendes, Fernando, Li, Li M., Karina Borges, Guerreiro, CAM, Borges, K, de Boer, Hanneke M., Prilipko, Leonid, Espíndola, Javier, Moacir A. Borges, Sander, Josemir W., Guerreiro, Carlos A.M., Borges, MA, Li, LM, Claudio T. Miranda, de Boer, HM, Prilipko, L, Hanneke M. de Boer, Fernandes, Paula T., Marques, Lucia H.N., Zanetta, Dirce M.T., Noronha, Ana L.A., Borges, Moacir A., Noronha, ALA, Li M. Li, Dirce M.T. Zanetta, Miranda, Claudio T., Sander, JW, Fernandes, PT, Zanetta, DMT, Fernando Cendes, Borges, Karina, Leonid Prilipko, Ana L.A. Noronha, Miranda, CT, Paula T. Fernandes, Marques, LHN, Cendes, F, Josemir W. Sander, Espiindola, J   +41 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source