Results 141 to 150 of about 118,836 (248)

Individualized antisense oligonucleotides for SCN2A-related developmental epileptic encephalopathy. [PDF]

Nat Med
Kim-McManus O, Mignon L, Douville J, Pu H, Parisien C, Glass S, Bennett CF, Celso J, Robbins K, Ung H, Olson H, Kingsmore SF, Petrou S, Crooke ST, Gleeson JG, Berry-Kravis E.   +15 more
europepmc   +1 more source

Revisiting the concept that interictal implies asymptomatic: Pulse wave amplitude drops uncover autonomic responses during generalized paroxysmal fast activities

Epilepsia, EarlyView.
Abstract Objective Interictal electroencephalographic (EEG) activities are generally considered asymptomatic. Pulse wave amplitude drop (PWAD) is a marker of autonomic nervous system (ANS) reactivity linked to cardiovascular risk. Generalized paroxysmal fast activity (GPFA) is a major EEG pattern in different epileptic conditions.
Julie Lévi‐Strauss, Valerio Frazzini, Claude Adam, Isabelle Gourfinkel‐An, Sophie Dupont, Vincent Navarro, Vi‐Huong Nguyen‐Michel   +6 more
wiley   +1 more source

Assessment of gabapentin efficacy in patients with KCNQ2-developmental epileptic encephalopathy. [PDF]

Sci Rep
Xiong J, You X, Li H, Chen C, Duan H, Chen S, Cao X, He F, Fei Y, Xiao Z, Peng J.   +10 more
europepmc   +1 more source

Cortical silent period following transcranial magnetic stimulation in epileptic patients

, 2000
Cortical silent period (SP) following transcranial magnetic stimulation is mainly due to cortical inhibitory mechanisms. SP may have a value for detecting inhibitory mechanisms in epileptic patients with or without treatment. The aim of this study was to
Altunhalka, A, Kirbas, DURSUN, Gul, Gülsen, Ertas, Nilgün   +3 more
core  

Programming of deep brain stimulation of the centromedian nucleus of the thalamus for drug‐resistant epilepsy: A meta‐analysis and proposed programming framework

Epilepsia, EarlyView.
Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes.
Mohammed A. AlQahtani, Michal Stern‐Zimmer, Puneet Jain, Suvasini Sharma, Alfonso Fasano, Alexander Rotenberg, George M. Ibrahim, Carolina Gorodetsky   +7 more
wiley   +1 more source

A Novel Gain-of-Function GLUL Variant Is Associated With Developmental and Epileptic Encephalopathy With Enlarged Perivascular Spaces. [PDF]

Hum Mutat
Wu T, He F, Ni X, Yin F, Peng J.
europepmc   +1 more source

Prediction of subsequent seizures after acute symptomatic seizures in critically ill children: A clinical–electroencephalographic model

Epilepsia, EarlyView.
Abstract Objective We aimed to determine the risk of subsequent seizure or epilepsy diagnosis after acute symptomatic seizures (ASyS) in critically ill children, evaluate whether antiseizure medication (ASM) use is associated with subsequent seizure/epilepsy diagnosis, and develop a simple Seizure/Epilepsy Risk Score to predict subsequent seizure ...
Nicholas S. Abend, France W. Fung, Darshana S. Parikh, Mark Ramos, Rui Xiao, Alexis A. Topjian   +5 more
wiley   +1 more source

Developmental and/or epileptic encephalopathy with spike-and-wave activation in sleep: Pathophysiological insights and treatment options. [PDF]

Epilepsia
Specchio N, Auvin S, Brunklaus A, De Giorgis V, Di Micco V, Gardella E, Jansen FE, Nabbout R, Pepi C, Rubboli G, Trivisano M, Curatolo P.   +11 more
europepmc   +1 more source

Incidence and impact of respiratory tract infections on outcomes in patients with status epilepticus: A 20‐year longitudinal observation

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to identify the incidence of respiratory tract infections (RTIs) in a large cohort of adult patients with status epilepticus (SE) and to characterize their associations with clinical features and outcome determinants.
Sebastian Berger, Sira M. Baumann, Urs Fisch, Lisa Hert, Pascale Grzonka, Sabina Hunziker, Stephan Rüegg, Sarah Tschudin‐Sutter, Raoul Sutter   +8 more
wiley   +1 more source

Developmental and/or Epileptic Encephalopathy with Spike-Wave Activation in Sleep: From Thalamocortical Mechanisms to Precision Therapy. [PDF]

Children (Basel)
Samanta D.
europepmc   +1 more source