Results 161 to 170 of about 8,267 (258)

The Effect of Physical Disability on Employment

Scottish Journal of Political Economy, EarlyView.
ABSTRACT The relationship between physical disability and employment is explored using microdata for older working‐age women in the 2016 Irish Census of Population and historical data on the incidence of infectious diseases. Two‐stage least squares and recursive bivariate probit estimations are employed to account for the potential endogeneity of ...
Irene Mosca
wiley   +1 more source

Hospital readmissions in children with new-onset infantile epileptic spasms syndrome. [PDF]

Epilepsia Open, 2023
Harini C, Yuskaitis CJ, Singh A, McHugh T, Liu S, DeLeo M, Gupta N, Marti C, Zhang B, Libenson MH, Berry JG.   +10 more
europepmc   +1 more source

The Expanding Clinical and Genetic Spectrum of Muscle Glycogen Storage Disease 0, (GSD0B)

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Glycogen storage disorders are a group of genetic disorders affecting glucose homeostasis in the body. Muscular glycogen stores are essential for liberating glucose for energy supply during bursts of activity and sustained muscle work. Muscle glycogen storage disease 0 (GSD0B) is associated with biallelic variants in GYS1 causing muscular ...
Sarah Donoghue, Smitha Kumble, Pontus Wasling, Lars Alberg, Pia Linton‐Dahlöf, Yilmaz Yildiz, İlker Ertuğrul, Terry Derks, Dwight Koeberl, Emmeline Lagrange, Sabrina Vergnaud, Lidia Pezzani, Maria Iascone, Zornitza Stark, Adam M. Bournazos, Sandra T. Cooper, Gittan Kollberg   +16 more
wiley   +1 more source

Real‐World Therapeutic Hypothermia for Neonatal HIE: Neurodevelopmental Outcomes and Predictors

Acta Paediatrica, Volume 114, Issue 11, Page 2874-2884, November 2025.
ABSTRACT Aim This study assessed neurodevelopmental outcomes in neonates with hypoxic‐ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH) outside randomised controlled trials (RCTs). It also aimed to identify predictors of outcomes and evaluate TH practices across centres.
Luca Bedetti, Licia Lugli, Isotta Guidotti, Maria Federica Roversi, Elisa Della Casa Muttini, Marisa Pugliese, Natascia Bertoncelli, Eugenio Spaggiari, Alessandra Todeschini, Gina Ancora, Sara Grandi, Giancarlo Gargano, Claudio Gallo, Mario Motta, Piero Catenazzi, Luigi Tommaso Corvaglia, Vittoria Paoletti, Agostina Solinas, Elisa Ballardini, Serafina Perrone, Sabrina Moretti, Marcello Stella, Alberto Berardi, Fabrizio Ferrari   +23 more
wiley   +1 more source

Predictive model for initial response to first-line treatment in children with infantile epileptic spasms syndrome. [PDF]

Ital J Pediatr
Ge W, Wan L, Wang Z, Fu L, Yang G.
europepmc   +1 more source

The fast‐dissociating D2 antagonist antipsychotic JNJ‐37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment

British Journal of Pharmacology, Volume 182, Issue 22, Page 5574-5595, November 2025.
Abstract Background and Purpose Pharmacological activation of neuronal M‐current mediated by Kv7 (Kv7.2–5) potassium channels is a validated mechanism for epilepsy treatment. However, since the market withdrawal of the prototype Kv7 activator retigabine, no Kv7 activator is clinically available for this condition.
Lidia Carotenuto, Oliver Keminer, Giusy Carleo, Andrea Zaliani, Antonio Leo, Rita Citraro, Giovambattista De Sarro, Nina Dirkx, Marcus Kaji, Sarah Weckhuysen, Jeanette Reinshagen, Vincenzo Barrese, Natascia Guida, Carmine Ostacolo, Francesco Miceli, Philip Gribbon, Maurizio Taglialatela   +16 more
wiley   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

Developmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1383-1408, November 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón, Nuria Carreras, Tobias Muehlbacher, Dídac Casas‐Alba, Roberta Arena, Paola Roca‐Llabrés, Juan Navarro‐Morón, Linda S. de Vries, Paul Govaert, the EurUS.Brain group, Thais Agut, Roberta Arena, Ana Alarcón, Juan Arnáez, Marco Bartocci, Isabel Benavente‐Fernández, María Carmen Bravo, Fernando Cabañas, Nuria Carreras, Olivier Claris, Jeroen Dudink, Monica Fumagalli, Alfredo García‐Alix, Paul Govaert, Sandra Horsch, Simón Lubián, Tobias Muehlbacher, Alessandro Parodi, Adelina Pellicer, Luca Ramenghi, Charles C. Roehr, Simone Schwarz, Sylke Steggerda, Eva Valverde   +33 more
wiley   +1 more source

Neurobehavioral deficits and a progressive ictogenesis in the tetrodotoxin model of epileptic spasms. [PDF]

Epilepsia, 2022
Le JT, Ballester-Rosado CJ, Frost JD, Swann JW.   +3 more
europepmc   +1 more source

Structural Basis of GABAB Receptor Activation during Evolution

Advanced Science, Volume 12, Issue 37, October 6, 2025.
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou, Shenglan Zhang, Cangsong Shen, Suyu Ji, Binqian Zou, Chanjuan Xu, Liang Li, Dandan Shen, Jiayin Liang, Haidi Chen, Philippe Rondard, Cheng Deng, Jun He, Yan Zhang, Jianfeng Liu   +14 more
wiley   +1 more source

Optimal lead time for treatment of infantile epileptic spasms syndrome-a secondary data analysis. [PDF]

Transl Pediatr
Ge W, Pang P, Zhang Z, Wan L, Yang G.
europepmc   +1 more source