Results 251 to 260 of about 2,345,783 (392)

Bradycardia is induced by hyperactivity of the vagus nerve and nucleus ambiguus during seizures propagating into the brainstem

Epilepsia Open, EarlyView.
Abstract Objective Seizure‐induced bradycardia and asystole have been documented by video‐EEG monitoring periods in patients with epilepsy. This cardiac dysfunction during or after seizures may contribute to sudden unexpected death in epilepsy (SUDEP). Abnormal neurocardiac function during seizures could potentially be caused by seizures propagating to
Chia‐Chu Chiang, B. P. Kotamraju, Dominique M. Durand   +2 more
wiley   +1 more source

MECP2 duplication syndrome-Typical EEG characteristics. [PDF]

Epileptic Disord
Otu W, Sudhakaran R, Garza-Garcia G, Parekh K, Sheikh IS.   +4 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Focal aware seizures manifesting as restless legs syndrome-like symptoms in a patient with periodic limb movement disorder. [PDF]

Epileptic Disord
Rasul A, Farooqi AM, Peters JD, Cho YW, Motamedi GK.   +4 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Efficacy and safety of cannabidiol in a single-center pediatric drug-resistant epilepsy cohort: a retrospective study. [PDF]

Front Neurol
Butera A, Spoto G, Ceraolo G, Grella M, Giunta I, Albertini ML, Consoli C, Sferro C, Spanò M, Di Rosa G, Nicotera AG.   +10 more
europepmc   +1 more source

De novo loss-of-function mutations in CHD2 cause a fever-sensitive myoclonic epileptic encephalopathy sharing features with Dravet syndrome.

American Journal of Human Genetics, 2013
A. Suls, Johanna A Jaehn, A. Kecskés, Y. Weber, S. Weckhuysen, D. Craiu, Aleksandra Siekierska, T. Djémié, T. Afrikanova, P. Gormley, S. von Spiczak, G. Kluger, C. Iliescu, T. Talvik, I. Talvik, C. Meral, H. Caglayan, B. G. Giraldez, J. Serratosa, J. Lemke, D. Hoffman-Zacharska, E. Szczepanik, N. Barišić, V. Komárek, H. Hjalgrim, R. Møller, T. Linnankivi, P. Dimova, P. Striano, F. Zara, C. Marini, R. Guerrini, C. Depienne, S. Baulac, G. Kuhlenbäumer, A. Crawford, A. Lehesjoki, P. D. de Witte, A. Palotie, H. Lerche, Camila V. Esguerra, P. de Jonghe, I. Helbig   +42 more
semanticscholar   +1 more source

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective To assess the efficacy and tolerability of fenfluramine (FFA) with concomitant potassium bromide (BR) in patients with Dravet syndrome (DS). Methods This multicenter retrospective study, conducted within the German compassionate use program, analyzed BR doses and serum levels before and after FFA initiation, adverse events (AEs ...
Milka Pringsheim, Gerhard Kluger, Adam Strzelczyk, Susanne Schubert‐Bast, Thomas Mayer, Benjamin Glauche, Hiltrud Muhle, Michael Alber, Hartwig Spors, Tilmann Polster, Regina Trollmann, Gerhard Kurlemann, Markus Berndt, Kerstin A. Klotz   +13 more
wiley   +1 more source

Landau-Kleffner Syndrome Can Herald the Diagnosis of GRIN2A Gene Mutation. [PDF]

Case Rep Pediatr
Ebrahim AK, Makhlooq JJ, Busehail MY.
europepmc   +1 more source

LANDAU–KLEFFNER SYNDROME (ACQUIRED EPILEPTIC APHASIA) WITH A FOCUS ON ELECTROENCEPHALOGRAPHIC CRITERIA

, 2016
К. Yu. Мukhin
openalex   +2 more sources