Results 281 to 290 of about 88,373 (350)

Add-on ketogenic diet versus antiseizure medications alone in children with developmental and epileptic encephalopathies: a prospective comparative cohort study. [PDF]

Front Neurol
Hu W, Li L, Zhao F, Su S, Zhang H, Li X.
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

A model-based cost-effectiveness estimates of hormonal therapy in Indian children with infantile epileptic spasms syndrome. [PDF]

Epilepsia Open
Devi N, Madaan P, Bharti SK, Sahu JK, Bansal D.   +4 more
europepmc   +1 more source

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies [PDF]

, 2018
Thio, Liu Lin, Weisenberg, Judith
core   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

One Size Does Not Fit All: Novel Individualized Use of Dexamethasone in Infantile Epileptic Spasms Syndrome. [PDF]

Neurol Ther
Kabak E, Leitner IC, Stark B, Gröppel G.   +3 more
europepmc   +1 more source

The Efficacy of Combined Lamotrigine and Levetiracetam Therapy in Epileptic Patients and Its Effects on Hippocampal Volume and Neuroinflammatory Response. [PDF]

J Inflamm Res
Li P, Qi A, Ma J, Li A, Sun Z.
europepmc   +1 more source

Successful Management of Cerebral Salt-Wasting Syndrome in a Child With Epileptic Encephalopathy: A Case Report. [PDF]

Clin Case Rep
Zhang R, Deng Y, Li W.
europepmc   +1 more source

Diagnosis and follow-up of a PCDH19 epilepsy patient. [PDF]

Psychiatr Genet
Chen Y, Xia Y, Chen L, Liu Z, Li B, Zhou K, Yue Y.   +6 more
europepmc   +1 more source