Results 71 to 80 of about 2,345,783 (392)

Relation of photosensitivity to epileptic syndromes. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1986
Photosensitivity is the most common mode of seizure precipitation. It is age-related, more frequent in females, and most often found in generalised epilepsies. Little is known about its relation to individual epileptic syndromes. This study on 1062 epileptic patients who had 4007 split screen video EEG investigations revealed that the relation to ...
P Wolf, R Goosses
openaire   +2 more sources

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Cytokines and neuro-specific proteins in viral encephalitis and convulsive syndrome in children. II. Convulsive syndrome

Инфекция и иммунитет, 2021
In this Section we provide new data on the pathogenetic factors in pediatric convulsive syndrome, including a prominent role of viral infection in developing seizures and epilepsy (EPL) in children, as evidenced by clinical and experimental studies ...
L. A. Alekseeva, G. F. Zheleznikova, E. Y. Gorelik, N. V. Sckripchenko, A. A. Zhirkov   +4 more
doaj   +1 more source

Optical mapping of neuronal activity during seizures in zebrafish [PDF]

, 2017
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology and improve our approaches to the development of new drugs.
Fornetto, C, M\ufcllenbroich, M. C, Mannaioni, G, Marchetto, Giulia, Masi, A, Pavone, F. S, Resta, F, Tiso, Natascia, Turrini, L, Vanzi, F., Vettori, Andrea   +10 more
core   +3 more sources

A phase 2, randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox–Gastaut syndrome (ELEKTRA)

Epilepsia, 2022
Dravet syndrome (DS) and Lennox–Gastaut syndrome (LGS) are rare treatment‐resistant childhood epilepsies classed as developmental and epileptic encephalopathies.
Cecil D. Hahn, Yuwu Jiang, V. Villanueva, M. Żołnowska, Dimitrios Arkilo, Samuel Hsiao, M. Asgharnejad, D. Dlugos   +7 more
semanticscholar   +1 more source

The Interplay between the Gut and Ketogenic Diets in Health and Disease

Advanced Science, EarlyView.
This review synthesizes current knowledge on the interaction between ketogenic diets and the gut, covering gut physiology, intestinal immunity, and the gut microbiome. It explores innovative methods for tailoring the diet to maximize benefits while reducing side effects. Emphasis is placed on gut‐mediated mechanisms as a critical interface between diet
Chunlong Mu, Jong M. Rho, Jane Shearer
wiley   +1 more source

Epileptic dyskinetic encephalopathy in KBG syndrome: Expansion of the phenotype

Epilepsy & Behavior Reports
KBG syndrome is characterised by developmental delay, dental (macrodontia of upper central incisors), craniofacial and skeletal anomalies. Since the identification of variants in the gene (ANKRD11) responsible for KBG syndrome, wider phenotypes are ...
Eoin P. Donnellan, Kathleen M. Gorman, Amre Shahwan, Nicholas M. Allen   +3 more
doaj   +1 more source

Ohtahara syndrome and IVF: A case report [PDF]

Acta Medica Iranica, 2000
Ohtahara syndrome or ealy infantile epileptic encephalopathy is a rare cause of epileptic seizures during infancy and represents the earliest type of age related symptomatic generalized epilepsies.
Ashrafi NR
doaj   +2 more sources

Wavelet analysis of epileptic spikes [PDF]

, 2003
Interictal spikes and sharp waves in human EEG are characteristic signatures of epilepsy. These potentials originate as a result of synchronous, pathological discharge of many neurons.
A. Babloyantz, Andrzej Kozik, Bruce J. West, C. Torrence, C.E. D’Attellis, C.J. Stam, F. Sartoretto, G. Widman, I. Clark, I.A. Rezek, J. Engel, J. Gotman, J. Gotman, J. Gotman, J. Gutiérrez, K. Lehnertz, L. Diambra, L. Ingber, L. Senhadji, M. Unser, M.C. Casdagli, M.J.A.M. van Putten, Miroslaw Latka, P. Jallon, P.L. Nunez, P.L. Nunez, S. Blanco, W.S. Pritchard, Ziemowit Was   +28 more
core   +2 more sources

Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome

Nature Communications, 2022
Dravet syndrome is a severe epileptic encephalopathy caused primarily by haploinsufficiency of the SCN1A gene. Repetitive seizures can lead to endurable and untreatable neurological deficits.
Nicholas Valassina, S. Brusco, Alessia Salamone, L. Serra, Mirko Luoni, S. Giannelli, Simone Bido, Luca Massimino, F. Ungaro, P. Mazzara, P. D’Adamo, G. Lignani, V. Broccoli, G. Colasante   +13 more
semanticscholar   +1 more source