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Fragility in epileptic networks: The epileptogenic zone

2017 American Control Conference (ACC), 2017
Epilepsy is a network phenomenon characterized by seizures that cause hypersynchronous activity of populations of neurons at the cortical level. In our previous work, we defined a seizure event as an outcome of a stable networked system switching to an unstable system.
Adam Li   +3 more
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Disconnecting epileptogenic zone is as effective as resection

Journal of Neurology, Neurosurgery & Psychiatry, 2013
Isolating an epileptogenic zone by disconnecting it from the rest of the brain is a principle that has gained more prominence in the last 15 years. Several variants of disconnection techniques (or deafferentation techniques) have been published, like the hemispherotomy procedures,1 ,2 but the principle of disconnection has also been used for other ...
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EEG Signal Classification for Epileptogenic Zone and Seizure Zone

2018
ElectroEncephaloGram (EEG) signals play an important role to identify epileptic disorders. Epilepsy is a neurological disorder that is an unexpected electrical disruption of the brain, because the activity of nerve cells in the brain becomes disrupted, causing people to experience “seizures.” Nowa-day, researcher works and focuses on automatic analysis
Hardika B. Gabani, Chirag N. Paunwala
openaire   +1 more source

Very high‐frequency oscillations: Novel biomarkers of the epileptogenic zone

Annals of Neurology, 2017
ObjectiveIn the present study, we aimed to investigate depth electroencephalographic (EEG) recordings in a large cohort of patients with drug‐resistant epilepsy and to focus on interictal very high‐frequency oscillations (VHFOs) between 500Hz and 2kHz. We hypothesized that interictal VHFOs are more specific biomarkers for epileptogenic zone compared to
Milan, Brázdil   +12 more
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Timing matters for accurate identification of the epileptogenic zone

Clinical Neurophysiology
Interictal biomarkers of the epileptogenic zone (EZ) and their use in machine learning models open promising avenues for improvement of epilepsy surgery evaluation. Currently, most studies restrict their analysis to short segments of intracranial EEG (iEEG).We used 2381 hours of iEEG data from 25 patients to systematically select 5-minute segments ...
Bartlomiej Chybowski   +11 more
openaire   +3 more sources

[Epileptogenic and non-epileptogenic zones: blood flow studies of temporo-limbic seizures].

Revue neurologique, 2008
To assess the contribution of ictal SPECT to the definition of the epileptogenic zone (EZ) prior to surgery in focal drug-resistant epilepsies, we investigated the effect of the timing of injection and seizure semiology on patterns of perfusion and cerebral blood flow changes (CBF) beyond the EZ.
S, Chassagnon   +5 more
openaire   +1 more source

Regional “Rigidity” of Background EEG Activity in the Epileptogenic Zone

Epilepsia, 1994
Summary: Spectral analysis of interictal background EEG activity recorded through foramen ovale (FO) electrodes during monitoring (mean 5.8 days per patient) was studied in 10 medically refractory complex partial seizure (CPS) patients who were candidates for epilepsy surgery. Data of the spectral analysis was plotted as compressed spectral array (CSA)
J, Wang, H G, Wieser
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Localization of epileptogenic zone based on time-varying effective networks

Epilepsy Research
Surgical resection of the epileptogenic zone (EZ) is an effective method for treating drug-resistant epilepsy. At present, the accuracy of EZ localization needs to be further improved. The characteristics of graph theory based on partial directed coherence networks have been applied to the localization of EZ, but the application of network control ...
Ning, Yin   +5 more
openaire   +2 more sources

Electrical Stimulation for Mapping of the Epileptogenic Zone

2018
Electrical cortical stimulation mapping (ECM) is a neurophysiological technique used to help identify the epileptogenic zone (area of brain responsible for a person’s epilepsy). ECM accomplishes this in two ways: (1) direct stimulation of a specified cortical area resulting in the patient’s habitual seizures and (2) the understanding of specific ...
Patrick Landazuri, Lorella Minotti
openaire   +1 more source

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