Results 61 to 70 of about 25,239 (336)

Offset analgesia as a marker of dysfunctional pain modulation in episodic and chronic migraine

open access: yesThe Journal of Headache and Pain
Background The offset analgesia phenomenon refers to the disproportionately large decrease in the perceived pain following a slight decrease in intensity of a noxious heat stimulus.
Giuseppe Cosentino   +8 more
doaj   +1 more source

Safety, Tolerability, and Pharmacokinetics of Galcanezumab, an Anti‐CGRP Antibody, in Healthy Chinese Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Galcanezumab is used in several regions, including the United States, Europe, and China, as a preventive treatment for migraine. This study aimed to evaluate the safety, tolerability, and pharmacokinetics (PK) of galcanezumab in healthy Chinese participants.
Jingjing Wang   +8 more
wiley   +1 more source

Propagation Structure of Intrinsic Brain Activity in Migraine without Aura

open access: yesBrain Sciences, 2022
Previous studies have revealed highly reproducible patterns of temporally lagged brain activity in healthy human adults. However, it is unknown whether temporal organization of intrinsic activity is altered in migraines or if it relates to migraine ...
Lingling Dai   +7 more
doaj   +1 more source

The therapeutic armamentarium in migraine is quite elderly. [PDF]

open access: yes, 2014
Global Burden of Disease 2010 study considers migraine as one of the most important noncommunicable diseases in the world, classifying it third in terms of global prevalence (14.70%): it sums up the 54.19% of all the years of life lived with disabilities
Martelletti, Paolo
core   +1 more source

Phenothiazine Derivatives and Their Impact on the Apoptosis Processes: A Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Phenothiazine derivatives have been used for decades as antipsychotic drugs in multiple mental health and physical conditions treatment (schizophrenia, mania in bipolar disorder, and psychosis). Epidemiological studies have shown that people with schizophrenia are less likely to suffer from cancer, which indicates the ability of antipsychotics
Michał Otręba   +4 more
wiley   +1 more source

Migraine and episodic Vertigo: a cohort survey study of their relationship

open access: yesThe Journal of Headache and Pain, 2019
Background and aim Migraine headache and vestibular-type vertigo co-occur in the general population about three times more often than expected by chance. Attacks of episodic vertigo (eV) are currently not recognized as migraine equivalents or variants in
Christian Lampl   +3 more
doaj   +1 more source

Prophylactic treatment can modify vascular risk biomarkers in high-frequency episodic and chronic migraine patients: a pilot study

open access: yesScientific Reports, 2023
To evaluate whether preventive treatment can modify endothelial and oxidative biomarkers of vascular disease risk in patients with high-frequency episodic and chronic migraine.
Cristina González Mingot   +10 more
doaj   +1 more source

Cluster headache in Greece: an observational clinical and demographic study of 302 patients. [PDF]

open access: yes, 2016
BackgroundCluster headache (CH) is considered the most excruciating primary headache syndrome; although much less prevalent than migraine, it is not rare as it affects more than 1/1000 people.
Rapoport, Alan M, Vikelis, Michail
core   +1 more source

Anxiety and Depression in Adults With Vestibular Disorders: A Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 85 studies (n = 764,403) found that adults with vestibular disorders have markedly higher rates and risks of anxiety and depression than controls. Prevalence was greatest in episodic conditions such as vestibular migraine and Ménière's disease.
Cory Hyun‐su Kim   +5 more
wiley   +1 more source

Management of migraine [PDF]

open access: yes, 1999
Migraine is a complex neurovascular disease characterised by episodic attacks of severe headache accompanied by autonomic and neurological symptoms. Two types of migraine have been identified: (1) common migraine, or migraine without aura, occurring in ...
Farrugia, Isabelle
core  

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