Results 81 to 90 of about 25,223 (248)

New Trends in Migraine Pharmacology: Targeting Calcitonin Gene–Related Peptide (CGRP) With Monoclonal Antibodies

open access: yesFrontiers in Pharmacology, 2019
Migraine is a common neurologic disorder characterized by attacks consisting of unilateral, throbbing headache accompanied by photophobia, phonophobia, and nausea which remarkably reduces the patients’ quality of life. Not migraine-specific non-steroidal
Damiana Scuteri   +9 more
doaj   +1 more source

A hypothetical proposal for association between migraine and Meniere's disease. [PDF]

open access: yes, 2020
Meniere's disease (MD) is a chronic condition affecting the inner ear whose precise etiology is currently unknown. We propose the hypothesis that MD is a migraine-related phenomenon which may have implications for future treatment options for both ...
Abouzari, Mehdi   +3 more
core  

P003. NSAIDs for symptomatic treatment of headache [PDF]

open access: yes, 2015
Background and aims Clinical observations suggest that the use of non-steroidal anti-inflammatory drugs (NSAIDs) for symptomatic treatment of headache is not in line with recommendations by international guidelines [1].
Affaitati, Giannapia   +8 more
core   +1 more source

CORRELATION BETWEEN MIGRAINE SEVERITY AND COMORBIDITIES IN EPISODIC MIGRAINE PATIENTS

open access: yesRomanian Journal of Neurology, 2015
Introduction. Migraine is an important cause of disability that affects the quality of life producing a substantial social impairment. Objectives. The aim of this study was to evaluate the correlation between migraine severity and comorbidities in patients with episodic migraine. Methods.
Adriana Bulboaca   +3 more
openaire   +2 more sources

Laparoscopically guided transversus abdominis plane block versus local wound infiltration analgesia in laparoscopic surgery for peritoneal endometriosis: A prospective randomized controlled double‐blinded LTAP‐trial

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
No statistically significant difference in the mean or median opioid consumption between laparoscopically guided transversus abdominis plane block (LTAP) and local wound infiltration analgesia (LWI) (control) analgesia for laparoscopic peritoneal endometriosis surgery.
Anna M. Terho   +6 more
wiley   +1 more source

Fremanezumab for the Preventive Treatment of Chronic Migraine. [PDF]

open access: yes, 2017
BACKGROUND: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a preventive treatment for migraine.
Aycardi, Ernesto   +9 more
core   +2 more sources

Episodic and Chronic Migraine in Primary Care [PDF]

open access: yesHeadache: The Journal of Head and Face Pain, 2019
Objective To inform migraine care model development by assessing differences between patients with chronic migraine (CM) and episodic migraine (EM) in the current state of treatment, disability, patient satisfaction, and quality improvement opportunities.
Nathan P. Young   +6 more
openaire   +2 more sources

DFN-02, Sumatriptan 10 mg Nasal Spray with Permeation Enhancer, for the Acute Treatment of Migraine: A Randomized, Double-Blind, Placebo-Controlled Study Assessing Functional Disability and Subject Satisfaction with Treatment. [PDF]

open access: yes, 2019
BackgroundThe commercial formulation of sumatriptan nasal spray is an effective option for migraine patients requiring or preferring a non-oral route of drug administration, but its utility is limited by poor absorption and tolerability issues. DFN-02, a
Brand-Schieber, Elimor   +3 more
core  

Triptans and CGRP blockade - impact on the cranial vasculature [PDF]

open access: yes, 2017
The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide ...
Alejandro Labastida-Ramírez   +9 more
core   +3 more sources

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

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