Results 161 to 170 of about 50,815 (199)

Sparse modeling of interactions enables fast detection of genome-wide epistasis in biobank-scale studies. [PDF]

Am J Hum Genet
Stamp J, Smith SP, Weinreich D, Crawford L.   +3 more
europepmc   +1 more source

Widespread epistasis shapes RNA polymerase II active site function and evolution. [PDF]

Nat Commun
Duan B, Qiu C, Sze SH, Kaplan C.
europepmc   +1 more source

Identifying new targets in the fight against opioids. [PDF]

Elife
Laezza F.
europepmc   +1 more source

From valleys to peaks: The role of evolvability in fitness landscape navigation. [PDF]

PNAS Nexus
Mehra P, Hintze A.
europepmc   +1 more source

Favorable epistasis in ancestral diterpene synthases promoted convergent evolution of a resin acid precursor in conifers. [PDF]

Proc Natl Acad Sci U S A
O'Donnell AJ, Pellatz PJ, Nichols CS, Gershenzon J, Peters RJ, Schmidt A.   +5 more
europepmc   +1 more source

Can classical statistics and deep learning converge on explainable, causally driven target discovery? [PDF]

DNA Res
Chen L.
europepmc   +1 more source

Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin. [PDF]

Nat Ecol Evol
Yu TC, Kikawa C, Dadonaite B, Loes AN, Englund JA, Bloom JD.   +5 more
europepmc   +1 more source

Multi-Genome-Wide association studies provide new insights into the genetic architecture of Varroa resistance in honeybees. [PDF]

BMC Genomics
Davoodi P, Razmkabir M.
europepmc   +1 more source

Genomic Prediction and Heritability Estimation for Daughter Pregnancy Rate in U.S. Holstein Cows Using SNP, Epistasis and Haplotype Effects. [PDF]

Int J Mol Sci
Yang R, Prakapenka D, Liang Z, Da Y.
europepmc   +1 more source