Results 131 to 140 of about 55,446 (204)
Fixation of mutators in asexual populations: the role of genetic drift and epistasis [PDF]
We study the evolutionary dynamics of an asexual population of nonmutators and mutators on a class of epistatic fitness landscapes. We consider the situation in which all mutations are deleterious and mutators are produced from nonmutators continually at a constant rate.
arxiv
Epistasis, an additive-by-additive interaction between quantitative trait loci, has been defined as a deviation from the sum of independent effects of individual genes.
Jan Bocianowski
doaj
Van Hove, H., Verschoren, A.
openaire +3 more sources
Functional bottlenecks can emerge from non-epistatic underlying traits [PDF]
Protein fitness landscapes frequently exhibit epistasis, where the effect of a mutation depends on the genetic context in which it occurs, \textit{i.e.}, the rest of the protein sequence. Epistasis increases landscape complexity, often resulting in multiple fitness peaks.
arxiv
Recombinant inbred line panels inform the genetic architecture and interactions of adaptive traits in Drosophila melanogaster. [PDF]
da Silva Ribeiro T+8 more
europepmc +1 more source
A Thermodynamic Cycle to Predict the Competitive Inhibition Outcomes of an Evolving Enzyme. [PDF]
Cetin E+3 more
europepmc +1 more source
Mitonuclear epistasis and mitochondrial disease [PDF]
Morrow, Edward H., Camus, M. Florencia
openaire +4 more sources
Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models. [PDF]
Tessele A+5 more
europepmc +1 more source