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The Geometry of Epistasis

1979
Let I be a set containing n elements. In Sec. 4 of the previous chapter we defined the subsets P = {x ∈ RI: xi ≽ 0 for i ∈ i} and Δ = {x ∈ P: Σ xi = 1). By the formula I. (4.1) we defined the Shahshahani metric, a Riemannian metric on P = {x ∈ RI: xi > 0 for i ∈ I}. It restricts to a metric on Δ = Δ ∩ P. In Table 4 of Sec. I.4 we defined the maps Ea(x)
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1905 Epistasis

2014
Genes act independently to influence organismal traits. Although Gregor Mendel studied some “dihybrid” crosses (those involving two genes) in his experiments on pea plants, the particular loci that he monitored proved to be independent in their effects on various of the plants’ phenotypes.
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Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme

Nature Chemical Biology, 2019
Gloria Yang   +9 more
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Linkage Disequilibrium or Epistasis?

Tissue Antigens, 1975
Fritz H. Bach, Miriam Secall
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Ecology shapes epistasis in a genotype–phenotype–fitness map for stick insect colour

Nature Ecology & Evolution, 2020
P. Nosil   +5 more
semanticscholar   +1 more source

Epistasis

2001
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