Results 261 to 270 of about 351,513 (313)

COMP promotes the progression of colorectal cancer by regulating epithelial mesenchymal transition. [PDF]

BMC Cancer
Huang H, Wang L, Gao S, Wang H.
europepmc   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

FABP4-mediated lipid droplet accumulation drives epithelial-mesenchymal transition and aggravates alveolar epithelial barrier disruption. [PDF]

Clin Transl Med
Shen Z, Qi Y, Chu M, Wu M, Feng C, Li X, Liu Z, Si L, Wang Y, Zhang J, Lu X, Lu P.   +11 more
europepmc   +1 more source

DNA‐Inspired Multi‐Functional Double‐Cross‐Linking Self‐Healing Hydrogel Promotes the Healing of Diabetic Wounds

Advanced Science, EarlyView.
A self‐healing hydrogel crosslinked with dynamic nucleobase‐mimetic bonds delivers curcumin‐loaded exosomes. It promotes diabetic wound healing via a synergistic combination of antibacterial, anti‐inflammatory, pro‐angiogenic, and immunomodulatory mechanisms, providing a comprehensive therapeutic approach.
Pu Yang, Yue Hu, Yikun Ju, Naihsin Hsiung, Juyi Ye, Anquan Jian, Lanjie Lei, Bairong Fang   +7 more
wiley   +1 more source

GLCCI1 alleviates airway remodeling in asthmatic mice by inhibiting ZEB1-mediated epithelial-mesenchymal transition. [PDF]

Respir Res
Yang Q, Wang W, Zhu G, Xun H, Xun Q.
europepmc   +1 more source

407 Autophagy May Facilitate Epithelial-Mesenchymal Transition in Eosinophilic Esophagitis and Genetically Engineered Mouse Models of Esophagitis

, 2013
Kelly A. Whelan, Sanders Chang, Amanda Muir, Joanne C. Masterson, Alain Benitez, Marie‐Pier Tétreault, Mary Ann S. Crissey, Jianping Kong, Phyllis A. Gimotty, Gary W. Falk, Jonathan P. Katz, John P. Lynch, Glenn T. Furuta, Mei‐Lun Wang, Hiroshi Nakagawa   +14 more
openalex   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Extracellular Vesicles Bearing Vimentin Drive Epithelial-Mesenchymal Transition. [PDF]

Mol Cell Proteomics
Parvanian S, Coelho-Rato LS, Silva MS, Sultana G, Venu AP, Devre PV, Modi MK, Eriksson JE.   +7 more
europepmc   +1 more source

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Epithelial-Mesenchymal Transition and Stress Adaptations Underlie Yttrium-90 Resistance in Liver Cancer Cell Lines. [PDF]

Cancer Res Commun
Zheleznyak A, Duraiyan D, Thunuguntla P, Camacho J, Wu S, Liu J, Weber JD, Thorek DLJ, Strnad BS, Fields RC, Ciorba MA, Yoon C, Blanc V, Davidson N, Silva-Fisher J, Malone CD.   +15 more
europepmc   +1 more source