Results 281 to 290 of about 351,513 (313)

Unraveling the role of HIF2α in melanoma progression and epithelial-mesenchymal transition. [PDF]

Sci Rep
Han Z, Gao Y, Li Z, Liu Z, Zhang J, Jing T, Xv Y, Miao G, Li X, Chen A.   +9 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Olivomycin A Targets Epithelial-Mesenchymal Transition, Apoptosis, and Mitochondrial Quality Control in Renal Cancer Cells. [PDF]

Antioxidants (Basel)
Hsieh CY, Liou YF, Shih YT, Tikhomirov AS, Shchekotikhin AE, Chueh PJ.   +5 more
europepmc   +1 more source

Critical parameters in a computational model of TGF-beta-induced epithelial mesenchymal transition. [PDF]

, 2018
Mendez, Mario J, Weinberg, Seth H
core   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition. [PDF]

Tob Induc Dis
Liu X, Sun S, He S, Xie L.
europepmc   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes. [PDF]

Hepat Med
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G.   +5 more
europepmc   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

[Retracted] PADI4‑mediated epithelial‑mesenchymal transition in lung cancer cells. [PDF]

Mol Med Rep
Liu M, Qu Y, Teng X, Xing Y, Li D, Li C, Cai L.   +6 more
europepmc   +1 more source