Results 181 to 190 of about 5,847,660 (310)

Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro. [PDF]

Clin Transl Sci
Moest WT, Lalai RA, Prins J, de Vries APJ, Wessels E, van Kooten C, Feltkamp MCW, Rotmans JI.   +7 more
europepmc   +1 more source

What are the best-demonstrated molecular mechanisms by which Campylobacter jejuni reaches the intestinal mucosa, moves through mucus, adheres, crosses the epithelial barrier, invades cells, and triggers inflammatory enteritis?

Tripdatabase
openalex   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Correction: FSP1 + fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells. [PDF]

Sci Rep
Sun L, Sun C, Liang Z, Li H, Chen L, Luo H, Zhang H, Ding P, Sun X, Qin Z, Zhao Y.   +10 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Hyperbaric oxygen treatment and toll-like receptor 5 in radioprotection of epithelial cells. [PDF]

PLoS One
Sallam L, Rychlíková L, Mölne J, Bergo MO, Naluai ÅT, Seeman-Lodding H, Oscarsson N, Giglio D.   +7 more
europepmc   +1 more source

Non-optimal temperature effects on respiratory epithelial cells in vitro: Relevance to climate change

Rui Deng, David Edwards, Chuang Hsiao-Chi, Brian Button, Peng Lu, Pankaj Kumar Bhavsar, Kian Fan Chung   +6 more
openalex   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The CTNNB1-TRIM28 complex governs hormone-induced RNA polymerase II dynamics in kidney epithelial cells. [PDF]

Proc Natl Acad Sci U S A
Jang HJ, Park E, Jung HJ, Kwon TH.
europepmc   +1 more source