Results 271 to 280 of about 1,809,231 (338)

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Correction: The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells.

J Am Soc Nephrol
Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Höhne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dieterich C, Fabretti F, Müller RU.   +19 more
europepmc   +1 more source

Deciphering the heterogeneity of epithelial cells in pancreatic ductal adenocarcinoma: implications for metastasis and immune evasion. [PDF]

World J Surg Oncol
Liu J, Li H, Lin X, Xiong J, Wu G, Ding L, Lin B.   +6 more
europepmc   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Protocol to infect differentiated human primary bronchial epithelial cells with live mycobacteria and determine intracellular load. [PDF]

STAR Protoc
Barclay AM, Walburg KV, Ninaber DK, Ottenhoff THM, Hiemstra PS, van der Does AM, Joosten SA.   +6 more
europepmc   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source

Electrotaxis disrupts patterns of cell-cell interactions of human corneal epithelial cells in vitro. [PDF]

Biophys J
Crossley RM, Martina-Perez SF.
europepmc   +1 more source

Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels

Advanced Functional Materials, EarlyView.
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco, Marc Falandt, Myriam Neumann, Martina Viola, Thibault Sampon, Marta G. Valverde, Anne Metje van Genderen, Silvia M. Mihaila, Cornelus F. van Nostrum, Bas G. P. van Ravensteijn, Riccardo Levato, Rosalinde Masereeuw, Tina Vermonden   +12 more
wiley   +1 more source

Meloxicam Alleviates Oxidative Stress Through Nrf2/HO-1 Activation in Bovine Endometrial Epithelial Cells. [PDF]

Vet Sci
Cui L, Duan J, Mao P, Zhong J, He S, Dong J, Liu K, Guo L, Li J, Wang H.   +9 more
europepmc   +1 more source