Results 101 to 110 of about 58,378 (265)

Histological AI‐Assisted Analysis Outperforms Pathologist Assessment in Predicting Disease Outcomes in PSC Patients

Hepatology Research, EarlyView.
Analyzing liver histology with AI assistance demonstrates superior prognostic performance compared to manual scoring in PSC. AI‐measured portal inflammation, fibrosis, biliary epithelium, and blood vessels predicted key clinical endpoints, such as liver transplantation due to end‐stage liver disease, highlighting the importance of liver histology as a ...
Anna M. Salonen, Iiris Nyholm, Linn Tähti, Matilda Sinkko, Darshan Kumar, Martti Färkkilä, Johanna Arola, Mikko P. Pakarinen, Sonja Boyd, Nelli Sjöblom   +9 more
wiley   +1 more source

Vermilionectomy for Actinic Cheilitis Treatment—Report of 03 Cases and Brief Literature Review

Case Reports in Dentistry
Actinic cheilitis (AC) is a common potentially malignant disorder that primarily affects the lower lip due to chronic ultraviolet B exposure. Severe epithelial dysplasia in AC carries a significant risk of progression to squamous cell carcinoma ...
Bruno Teixeira Gonçalves Rodrigues, Eduardo Martins Falcão, Caroline Cavaignac Silva, Paula Granha Porto, Ana Carolina Silva Custódio, Allan Ribeiro Bastos, Verônica dos Santos Lopes Serrano, Henrique Martins da Silveira, Danilo Passeado Branco Ribeiro, Mônica Simões Israel   +9 more
doaj   +1 more source

Correlation between computer-assisted quantitative autofluorescence imaging results and the pathological grading of oral epithelial dysplasia in oral leukoplakia

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To explore the correlation between the quantitative results of autofluorescence imaging under computer assistance and the grade of epithelial dysplasia in oral leukoplakia.Methods·From April 2016 to January 2024, 357 patients with oral ...
LI Chenxi, WANG Zirui, JIN Tianhao, ZHOU Zengtong, TANG Guoyao, SHI Linjun   +5 more
doaj   +1 more source

Diagnostic impact and reproducibility of p53 immunohistochemistry in Barrett's oesophagus: results of the Dutch Esophageal Pathology Panel (DEPP)

Histopathology, EarlyView.
Structured p53‐IHC in Barrett's oesophagus supports diagnostic decision‐making. In 1,146 cases, agreement between referring hospitals and the expert panel was moderate‐to‐substantial (κ = 0.61), with 24.2% of p53‐based classifications revised. Interobserver agreement among expert pathologists was substantial (κ = 0.65).
Ylva A. Weeda, Sarah M. Issa, Hans Halfwerk, Michel Botros, Onno J. de Boer, Lodewijk A. Brosens, Michail Doukas, Gursah Kats‐Ugurlu, Fiebo ten Kate, Jaap van der Laan, Ineke van Lijnschoten, Ariadne H. A. G. Ooms, Lindsey Oudijk, Rachel S. van der Post, Mihaela G. Raicu, Bert Timmer, Myrtle J. van der Wel, Sybren L. Meijer   +17 more
wiley   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion

Histopathology, EarlyView.
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang, Karen L. Talia, W. Glenn McCluggage, Robert A. Soslow, Bin Yang   +4 more
wiley   +1 more source

A Comparative Study on HER2/neu Expression in Normal Mucosa, Epithelial Dysplasia and Oral Squamous Cell Carcinoma

مجله دانشکده دندانپزشکی اصفهان, 2010
Introduction: HER2/neu is a proto-oncogene with a homologous sequence associated with epidermal growth factor. However the role of HER2/neu in Oral Squamous Cell Carcinoma (OSCC) remains controversial.
Safoura Seifi, Shahriar Shafaei, Kamran Nosrati, Behzad Ariaeifar   +3 more
doaj  

Soft‐Tissue Augmentation During Implant Placement in the Aesthetic Zone: Clinical, Radiographic, Histological and Patient‐Reported Outcomes From a Randomised Controlled Trial Using Connective Tissue Graft and a Volume‐Stable Collagen Matrix

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the clinical, radiographic, histological and patient‐reported outcome measures (PROMs) of soft‐tissue augmentation (STA) during implant placement in the aesthetic zone using a connective tissue graft (CTG) or a volume‐stable collagen matrix (VCMX). Materials and Methods In this three‐arm randomised controlled trial, 25 patients
Louiza Papantonatou, Leonidas Batas, Antigoni Delantoni, Eleutherios Anagnostou, Ioannis Vouros   +4 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, EarlyView.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source

Differences in the Gastric Microbiotas of Neighboring Populations With Divergent Risks of Gastric Cancer

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Although Helicobacter pylori plays a central role in gastric cancer (GC), other microorganisms involved in gastric dysbiosis may also impact carcinogenesis. We aimed to characterize gastric dysbiosis and its role in the transition from non‐atrophic gastritis (NAG) to gastric premalignant lesions (GPLs) in two populations from Nariño,
Juan Camilo Caguazango, Karla Vinasco, Isidora Simovic, Yomaira Yépez Caicedo, Marino Coral Bedoya, Nadeem O. Kaakoush, Natalia Castaño‐Rodríguez   +6 more
wiley   +1 more source