Results 81 to 90 of about 58,378 (265)

Chemopreventive Effect of Bitter Melon (Momordica charantia) Juice on Pancreatic Carcinogenesis in LSL‐KrasG12D/+; p48Cre/+ Mice

Molecular Carcinogenesis, EarlyView.
ABSTRACT Herein, using the LSL‐KrasG12D/+; p48Cre/+ transgenic mouse model [that recapitulates the full spectrum of human disease, progressing from early pancreatic intraepithelial neoplasia lesions to invasive pancreatic ductal adenocarcinoma (PDAC)], we determined the chemopreventive effect of long‐term (chronic) administration of Bitter Melon Juice (
Lakshmi Sai Pratyusha Bugata, Deepanshi Dhar, Rama Kant, Robin Kumar, Md. Imtiazul Kabir, Chapla Agarwal, Rajesh Agarwal, Komal Raina   +7 more
wiley   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

Pediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu, Wen Tan, Xiao Yang, Tingting Luo, Chenghao Mei, Huaqin Bu, Jinhua Ma, Chao Gong, Li Zhong, Ou Zhou, Daiyin Tian   +10 more
wiley   +1 more source

Caracterización histopatológica de la leucoplasia bucal en La Habana durante 10 años Histopathological characterization in the leukoplakia buccalis in Havana during 10 years

Revista Cubana de Estomatología, 2011
La displasia epitelial es considerada el más fuerte predictor histológico de la futura transformación maligna de la leucoplasia bucal. El objetivo del presente trabajo fue determinar la presencia y severidad de la displasia epitelial y su asociación con ...
Zenia Batista Castro, Irene Rodríguez Pérez, Josefa Miranda Tarragó, Enrique Rengifo Calzado, Teresita Rodríguez Obaya, Mónica Elena Fernández Jiménez   +5 more
doaj  

Histological and Immunohistochemical Characterization of Keratotic White Lesions in the Oral Cavity: A Cross-Sectional Study.

The Egyptian Journal of Histology
Background: Oral keratotic white lesions represent a diverse group of conditions, ranging from benign to possibly malignant disorders. Among these, oral epithelial dysplasia (OED) is a crucial histological marker for assessing the risk of malignant ...
Angom Manitombi Devi, Manish Singh Ahuja, Debasis Bandopadhyay, Divya Shelly, Alok Acharya, subhash B   +5 more
doaj   +1 more source

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

Small, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre, Elisabeth Mayerhoefer, Julia Puck, Himalaya Parajuli, Lorena Larios Salazar, Paul Johan Høl, Ridhima Das, Patrick Roth, Christian Arvei Moen, Ulrich Schatzschneider, Line Bjørge, Daniela Elena Costea, Anke Krueger   +12 more
wiley   +1 more source

Radiographic Screening of Wild and Semi‐Wild Cape Ground Squirrels (Geosciurus inauris) for the Presence of Peri‐Apical Masses Associated With Elodont Incisor Teeth

Zoo Biology, EarlyView.
Peri‐apical masses were absent in both wild and semi‐wild Cape ground squirrels, despite dietary differences and minor incisor trauma. These findings suggest such lesions are rare outside captivity and not induced by low‐fiber diets alone, adding to the literature on environmental and dietary risk factors in elodont tooth pathology.
Quintin Norval, Adrian Tordiffe, Gerhard Steenkamp   +2 more
wiley   +1 more source

Human papillomavirus persistence and clearance in women living with HIV: A five‐year retrospective analysis from an Italian university center

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In women living with HIV, HPV clearance occurred after a mean of approximately 2 years under antiretroviral therapy. Baseline positivity for the high‐risk HPV pool was associated with delayed clearance, suggesting that HPV genotype may influence viral persistence more than immunovirological status in clinically stable patients.
Annunziata Carlea, Dario Colacurci, Giorgia D'Apice, Laura Letizia Mazzarelli, Massimiliano Pellicano, Luigi Falco, Ginevra Sepe, Oriana Imperatore, Giuseppe Maria Maruotti, Maurizio Guida, Laura Sarno   +10 more
wiley   +1 more source

Budesonide and Surfactant Therapy Versus Surfactant Alone on Incidence of Lung Disease in Preterm Infants (BEST Lung): Study Protocol for a Systematic Review and Individual Participant Data Meta‐Analysis With Nested Prospective Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Introduction Bronchopulmonary dysplasia (BPD) is a leading cause of morbidity and mortality in preterm infants. Combining surfactant with budesonide has been proposed to prevent BPD, but results from existing randomised controlled trials (RCTs) are conflicting.
James X. Sotiropoulos, Brett J. Manley, Sol Libesman, Namasivayam Ambalavanan, Abhik Das, Christopher J. D. Mckinlay, Nalinikanta Panigrahy, Melinda Cruz, David Nguyen, Jonathan Williams, Peter Davis, Kylie E. Hunter, Anna Lene Seidler   +12 more
wiley   +1 more source

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source