Results 61 to 70 of about 93,692 (302)

Fluorescence lifetime spectroscopy of tissue autofluorescence in normal and diseased colon measured ex vivo using a fiber-optic probe

open access: yes, 2013
We present an ex vivo study of temporally and spectrally resolved autofluorescence in a total of 47 endoscopic excision biopsy/resection specimens from colon, using pulsed excitation laser sources operating at wavelengths of 375 nm and 435 nm.
Chorvat   +65 more
core   +1 more source

CO2 lasers in the management of potentially malignant and malignant oral disorders [PDF]

open access: yes, 2012
The CO2 laser was invented in 1963 by Kumar Patel. Since the early 1970s, CO2 laser has proved to be an effective method of treatment for patients with several types of oral lesions, including early squamous cell carcinoma.
Hamdoon, Z, Hopper, C, Jerjes, W
core   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

Expression Profiles of GILZ and SGK-1 in Potentially Malignant and Malignant Human Oral Lesions

open access: yesFrontiers in Oral Health, 2021
Glucocorticoid-induced leucine zipper and serum-glucocorticoid-regulated kinase-1 (SGK-1) are major glucocorticoid-inducible proteins. Recent studies indicate the local production of cortisol in oral mucosa, which can impact the tissue generation of ...
Mahmood S. Mozaffari, Rafik Abdelsayed
doaj   +1 more source

Intra-operative point-of-procedure delineation of oral cancer margins using optical coherence tomography. [PDF]

open access: yes, 2019
ObjectivesSurgical margin status is a significant determinant of treatment outcome in oral cancer. Negative surgical margins can decrease the loco-regional recurrence by five-fold.
Agarwal, Sagar   +12 more
core  

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions [PDF]

open access: yes, 2016
An exact classification of precancerous stages of colorectal polyps might improve therapy and patients´ outcome. Here we investigate the association between grade of dysplasia and Matrix metalloproteinase-13 (MMP-13) expression in 137 biopsies from ...
Churin, Yuri   +7 more
core   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

A Case of Solitary Nonvascularized Corneal Epithelial Dysplasia

open access: yesCase Reports in Ophthalmological Medicine, 2016
Background. Epithelial dysplasia is categorized as conjunctival/corneal intraepithelial neoplasia which is a precancerous lesion. The lesion is usually developed at the limbal region and grows towards central cornea in association with neovascularization
Tomoya Morii   +6 more
doaj   +1 more source

Mast cells and factor XIIIa+ dendrocytes in actinic cheilitis and lip squamous cell carcinoma [PDF]

open access: yesBrazilian Oral Research
There is an interaction between dendrocytes and mast cells in the skin. However, in elastosis-related diseases such as actinic cheilitis (AC) and lower lip squamous cell carcinoma (LLSCC), this interaction remains unknown. We investigated the presence of
Isadora Luana Flores   +12 more
doaj   +1 more source

Current challenges and the diagnostic pitfalls in the grading of epithelial dysplasia in oral potentially malignant disorders: A review

open access: yesJournal of Oral Biology and Craniofacial Research, 2020
Oral cancer is one of the common cancers in the world causing high morbidity. Development of cancer is preceded by certain asymptomatic clinical lesions and conditions all together known as ‘oral potentially malignant disorders’.
Sonia Gupta   +2 more
doaj   +1 more source

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