Results 41 to 50 of about 58,378 (265)

Oral epithelial dysplasia and aphthous ulceration in a patient with ulcerative colitis: a case report

BMC Oral Health, 2023
Background Ulcerative colitis is a chronic inflammatory disease with apparent extraintestinal manifestations, including in the oral cavity. Oral epithelial dysplasia, an exclusive histopathological diagnosis that is used to predict malignant ...
Kai Sun, Rong-Hui Xia
doaj   +1 more source

Deep learning approach to detect high-risk oral epithelial dysplasia: A step towards computer-assisted dysplasia grading

Advances in Human Biology, 2023
Introduction: Oral epithelial dysplasia (OED) is associated with high interobserver and intraobserver disagreement. With the exponential increase in the applicability of artificial intelligence tools such as deep learning (DL) in pathology, it would now ...
C Nandini, Shaik Basha, Aarchi Agarawal, R Parikh Neelampari, Krishna P Miyapuram, R Jadeja Nileshwariba   +5 more
doaj   +1 more source

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Nucleostemin upregulation and STAT3 activation as early events in oral epithelial dysplasia progression to squamous cell carcinoma

Neoplasia: An International Journal for Oncology Research, 2021
Most low-grade oral epithelial dysplasia remains static or regress, but a significant minority of them (4–11%) advances to oral squamous cell carcinoma (OSCC) within a few years.
Madeleine Crawford, Xiaoqin Liu, Yi-Shing L Cheng, Robert YL Tsai   +3 more
doaj   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

A Case of Solitary Nonvascularized Corneal Epithelial Dysplasia

Case Reports in Ophthalmological Medicine, 2016
Background. Epithelial dysplasia is categorized as conjunctival/corneal intraepithelial neoplasia which is a precancerous lesion. The lesion is usually developed at the limbal region and grows towards central cornea in association with neovascularization
Tomoya Morii, Takayoshi Sumioka, Ai Izutani-Kitano, Yukihisa Takada, Yuka Okada, Winston W.-Y. Kao, Shizuya Saika   +6 more
doaj   +1 more source

Mast cells and factor XIIIa+ dendrocytes in actinic cheilitis and lip squamous cell carcinoma [PDF]

Brazilian Oral Research
There is an interaction between dendrocytes and mast cells in the skin. However, in elastosis-related diseases such as actinic cheilitis (AC) and lower lip squamous cell carcinoma (LLSCC), this interaction remains unknown. We investigated the presence of
Isadora Luana Flores, José Alcides Almeida de Arruda, Thamiris de Castro Abrantes, Thiago de Oliveira Gamba, Aline Correa Abrahão, Ana Lia Anbinder, Jaqueline Lemes Ribeiro, Ana Carolina Uchoa Vasconcelos, Bruno Augusto Benevenuto de Andrade, Maria Cassia Ferreira de Aguiar, Ana Paula Neutzling Gomes, Lucas Guimarães Abreu, Ricardo Alves Mesquita   +12 more
doaj   +1 more source

Epithelial dysplasia in oral cavity.

Iranian journal of medical sciences, 2014
Among oral lesions, we encounter a series of malignant epithelial lesions that go through clinical and histopathologic processes in order to be diagnosed. Identifying these processes along with the etiology knowledge of these lesions is very important in prevention and early treatments.
Samaneh Shirani, Neda Kargahi, Sayed Mohammad Razavi, Solmaz Homayoni   +3 more
openaire   +2 more sources

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Histomorphometric analysis of vascularity in oral epithelial dysplasia

Journal of Dr. NTR University of Health Sciences, 2016
Context: Potentially malignant disorders such as leukoplakia and erythroplakia are often associated with dysplastic changes that have an increased risk for malignant transformation.
Sanapala Venkata Naga Sashi Kiran, Sri Lalitha Kaja, Kiran Kumar Kattapagari, Poosarla Chandra Shekar, Chitturi Ravi Teja, Baddam Venkat Ramana Reddy   +5 more
doaj   +1 more source