Background: Cigarette smoke contains various carcinogenic substances such as polycyclic aromatic hydrocarbons and nitrosamines. These chemicals not only have the potential to damage DNA, but can also induce genetic mutations and activate genes that ...
Dorisna Prijaryanti +4 more
doaj +1 more source
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. [PDF]
Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), graft-versus-host disease (GVHD), and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are common human gastrointestinal diseases that share inflammation as a key
Bortner, James D +6 more
core +2 more sources
Etiology and pathogenesis of cervical intraepithelial neoplasia (review of foreign literature)
Cervical intraepithelial neoplasia (CIN) is atypical transformation of squamos epithelium without stromal invasion predictive of cervical cancer. According to the World Health Organization (2014), there is mild cervical epithelial neoplasia (CIN I; mild
S. A. Levakov +2 more
doaj +1 more source
Epithelial Squamous Metaplasia and Dysplasia in Inflammatory Nasal Polyps: An Observational Study
Nasal polyposis (NP) is characterized by polypoid outgrowths of chronically inflamed respiratory mucosa. The presence of squamous metaplasia and dysplasia on the mucosal surface of nasal polyps (NPs) represents different manifestations of epithelial ...
Aleksandar Perić MD, PhD +3 more
doaj +1 more source
Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia : a case-control and immunohistochemical study [PDF]
PMID: 22824379 [PubMed - indexed for MEDLINE] PMCID: PMC3500224 Free PMC ArticlePeer reviewedPublisher ...
Basavaraju, Umesh +6 more
core +1 more source
Oral Epithelial Dysplasia and Premalignancy [PDF]
Leukoplakia and erythroplakia are two entities under the moniker of "oral potentially malignant disorders" that are highly associated with the presence of oral epithelial dysplasia (OED) at first biopsy, while lesions of submucous fibrosis develop OED after being present for years.
openaire +2 more sources
Expression of p63 in potentially malignant and malignant oral lesions
Background: p63, a member of p53 family, known to be expressed in embryonic tissues and basal regenerative layers of many epithelial tissues in the adult, is also expressed in various benign and malignant lesions of body including lesions of oral cavity.
Anju Sinha +5 more
doaj +1 more source
Histomorphometric Analysis of Angiogenesis using CD31 Immunomarker and Mast Cell Density in Oral Premalignant and Malignant Lesions: A Pilot Study [PDF]
Introduction: Mast cells have been implicated in promoting angiogenesis in malignant tumors of lung, oesophagus and breast, but there are few studies on Oral Squamous Cell Carcinomas (OSCC).
M Jyothsna, M Rammanohar, Kiran Kumar
doaj +1 more source
Aim: To evaluate the expression of E-cadherin (E-cad) in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Material and Method: Immunohistochemistry was used to detect E-cad expression in 20 cases each of normal oral mucosa, oral ...
Jaishree Sharma +5 more
doaj +1 more source
Association of Syndecan-1 immunoexpression with epithelial dysplasia in oral verrucous carcinoma
Background: Oral verrucous carcinoma (OVC) is an uncommon variant of well-differentiated squamous cell carcinoma with an excellent prognosis. Epithelial dysplasia in OVC is a sign of a poorer prognosis.
Md. Akhtaruzzaman +4 more
doaj +1 more source

