Results 11 to 20 of about 93,692 (302)

Nucleostemin upregulation and STAT3 activation as early events in oral epithelial dysplasia progression to squamous cell carcinoma

Neoplasia: An International Journal for Oncology Research, 2021
Most low-grade oral epithelial dysplasia remains static or regress, but a significant minority of them (4–11%) advances to oral squamous cell carcinoma (OSCC) within a few years.
Madeleine Crawford, Xiaoqin Liu, Yi-Shing L Cheng, Robert YL Tsai   +3 more
doaj   +3 more sources

Intestinal epithelial dysplasia (tufting enteropathy) [PDF]

Orphanet Journal of Rare Diseases, 2007
Intestinal epithelial dysplasia (IED), also known as tufting enteropathy, is a congenital enteropathy presenting with early-onset severe intractable diarrhea causing sometimes irreversible intestinal failure. To date, no epidemiological data are available, however, the prevalence can be estimated at around 1/50,000-100,000 live births in Western Europe.
de Serres Natacha, Ruemmele Frank, Salomon Julie, Goulet Olivier, Brousse Nicole   +4 more
openaire   +3 more sources

Intestinal epithelial dysplasia

Pacific Medical Journal, 2020
The article presents a clinical case of intestinal epithelial dysplasia (tufting enteropathy), a rare disease which relates to congenital diarrheas, has a particular clinical presentation and is life-threating. The diagnosis was confirmed by histological examination and electronic microscopy of mucous membrane of small intestine. Additional evidence is
T. E. Taranushenko, E. M. Vasilyeva, E. V. Antsiferova, L. N. Karpova, Y. S. Shamova   +4 more
openaire   +2 more sources

Expression of Ki-67, p53, α-SMA and COX-2 in lichen planus and related lesions: A pilot study

Journal of Oral Biology and Craniofacial Research, 2019
Background: Researchers have struggled to understand the natural history of lesions presenting with both lichenoid features and epithelial dysplasia.
D.S. Sanketh, Karuna Kumari, Roopa S. Rao, Vanishree C. Haragannavar, Sachin C. Sarode, Gargi S. Sarode, A. Thirumal Raj, Shankargouda Patil   +7 more
doaj   +1 more source

Comparison of expression of myofibroblasts in normal oral mucosa, oral epithelial dysplasia, and oral squamous cell carcinoma using α-SMA and vimentin: An immunohistochemical study

Journal of Family Medicine and Primary Care, 2020
Background: Myofibroblasts are thought to play critical roles in inflammation, growth, repair, premalignancy, and malignancy. This study was done to evaluate, compare and co- relate the progressive increase in the immunohistochemical expression of ...
Amani Mahajan, Andleeb Manhas, Tania Aneja, Swati Parhar, Priyanka Kumari, Anubhuti, Harkanwal P Singh   +6 more
doaj   +1 more source

Morphometric analysis of suprabasal cell layer in oral epithelial dysplasia: A computer-assisted microscopic study

Journal of Pharmacy and Bioallied Sciences, 2020
Background: Oral leukoplakia is the most common precancerous lesion. Various grading systems based on histological findings have been proposed for dysplasia.
Viswanathan Prema, Thomson Thomas, Prasad Harikrishnan, Mani Viswanathan, Kenniyan Kumar Srichinthu, Krishnan Rajkumar   +5 more
doaj   +1 more source

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé, Caulin, Carlos, Chabaud, Sylvie, Foy, Jean-Philippe, Goudot, Patrick, Hong, Waun Ki, Lachuer, Joël, Lang, Wenhua, Lavergne, Emilie, Le Texier, Vincent, Lippman, Scott M, Perol, David, Saintigny, Pierre, Thomas, Emilie, Tortereau, Antonin   +14 more
core   +1 more source

Suprabasal expression of Ki-67 as a marker for the severity of oral epithelial dysplasia and oral squamous cell carcinoma

Contemporary Clinical Dentistry, 2013
Background: Transition of the normal oral epithelium to dysplasia and to malignancy is featured by increased cell proliferation. To evaluate the hypothesis of distributional disturbances in proliferating and stem cells in oral epithelial dysplasia and ...
Nidhi Dwivedi, Shaleen Chandra, Bina Kashyap, Vineet Raj, Akhil Agarwal   +4 more
doaj   +1 more source

Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia. [PDF]

PLoS ONE, 2016
Lysophosphatidic acid (LPA) acts on LPA2 receptor to mediate multiple pathological effects that are associated with tumorigenesis. The absence of LPA2 attenuates tumor progression in rodent models of colorectal cancer, but whether overexpression of LPA2 ...
Michihiro Yoshida, Peijian He, C Chris Yun   +2 more
doaj   +1 more source

bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice [PDF]

, 2015
Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibility
Abuderman, A A, Burkitt, M D, Duckworth, C A, O'Reilly, L A, Pritchard, D M, Williams, J M   +5 more
core   +2 more sources