Results 161 to 170 of about 56,845 (265)

A Review on Image Processing and Fractal Analysis in Oral Potentially Malignant Disorders

Oral Diseases, EarlyView.
ABSTRACT Aim The clinical evaluation of patients with oral potentially malignant disorders is primarily based on physical examination and observable clinical features. Clinical photographs play a key role in patient monitoring and help identify signs that may indicate malignant transformation.
André Goulart Poletto, Flaviana Silva de Souza, Lilian Bezerra, Thiago Pires Claudio, Jesse Parente Tocantins, Helena Miguel Cotter, Riéli Elis Schulz, Karin Berria Tomazelli, Elena Riet Correa Rivero, Fabio Luiz Coracin, Gustavo Davi Rabelo   +10 more
wiley   +1 more source

Metagenomic Evaluation of Oral Microbiota in Patients Affected by Oral Lichen Planus: A Pilot Study

Oral Diseases, EarlyView.
ABSTRACT Objective To characterize the oral bacterial and fungal microbiota of symptomatic oral lichen planus patients undergoing topical corticosteroid therapy and to explore microbial patterns potentially associated with subsequent oral candidiasis. Methods Twelve patients with clinically and histologically confirmed OLP were enrolled.
A. Dormiente, L. Mancabelli, M. Ventura, G. Longhi, G. Mergoni, M. Manfredi   +5 more
wiley   +1 more source

Cutaneous Ciliated Cyst of the Ear

Pediatric Dermatology, EarlyView.
ABSTRACT Cutaneous ciliated cysts are rare benign lesions initially observed exclusively in the lower extremities of young females. Since their first descriptions, there have been numerous case reports of the entity occurring in males and females, in varying anatomical locations. Here, we present a case of cutaneous ciliated cyst reported for the first
Allan Fong, Andrew H. Huang, Jonathan Bush   +2 more
wiley   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

The Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Nonavalent HPV vaccine to prevent recurrent anal or vulvar high‐grade squamous intraepithelial lesions (VIVA trial): A randomized, double‐blind, placebo‐controlled trial

International Journal of Cancer, Volume 158, Issue 11, Page 2983-2994, 1 June 2026.
What's new? Anal and vulvar high‐grade squamous intraepithelial lesions (HSILs) frequently recur following treatment. Additional genital and anal procedures, however, can be distressing for patients and are potentially disfiguring. This trial assessed whether the 9‐valent human papillomavirus (9vHPV) vaccine reduces HSIL recurrence risk or HPV ...
Helen C. Stankiewicz Karita, Amalia S. Magaret, David R. Doody, Jeffrey T. Schouten, Constance Mao, Warner K. Huh, Verena S. Grieco, Matthew A. Seymour, Dana Varon, Kelly H. Shrader, Long Fu Xi, Denise A. Galloway, Anna Wald, Margaret M. Madeleine   +13 more
wiley   +1 more source

QuPath for automated analysis of digital images of oral epithelial dysplasia. [PDF]

J Oral Maxillofac Pathol
Belaldavar C, Angadi PV, Mudenagudi U.
europepmc   +1 more source

Distribution and prognostic value of T‐cells in primary colorectal cancer and adjacent non‐tumor mucosa in stage IV versus stage I–III patients

International Journal of Cancer, Volume 158, Issue 10, Page 2760-2770, 15 May 2026.
What's New? While colonic mucosa lymphocytes have been quantified in the context of inflammatory diseases, T‐cells in non‐tumor mucosa adjacent to colorectal cancer remain understudied. This study found that in stage IV colorectal cancer (synchronous liver metastasis), higher Foxp3+ T‐cell density and Foxp3+/CD4+ and Foxp3+/CD8+ T‐cell ratios in non ...
Esraa Ali, Wenjing Ye, Sergii Pavlov, Lenka Červenková, Filip Ambrozkiewicz, Ondřej Vyčítal, Petr Hošek, Ondřej Daum, Václav Liška, Kari Hemminki, Andriy Trailin   +10 more
wiley   +1 more source

Correction: Exploring the microbiome of oral epithelial dysplasia as a predictor of malignant progression. [PDF]

BMC Oral Health
Wright RJ, Pewarchuk ME, Marshall EA, Murray B, Rosin MP, Laronde DM, Zhang L, Lam WL, Langille MGI, Rock LD.   +9 more
europepmc   +1 more source