Results 1 to 10 of about 1,813,651 (244)

Current challenges and the diagnostic pitfalls in the grading of epithelial dysplasia in oral potentially malignant disorders: A review

Journal of Oral Biology and Craniofacial Research, 2020
Oral cancer is one of the common cancers in the world causing high morbidity. Development of cancer is preceded by certain asymptomatic clinical lesions and conditions all together known as ‘oral potentially malignant disorders’.
Sonia Gupta, Manveen Kaur Jawanda, GS Madhushankari   +2 more
doaj   +3 more sources

E-Cadherin is a diagnostic biomarker in the progression of oral epithelial dysplasia to squamous cell carcinoma [PDF]

Journal of Oral Biology and Craniofacial Research
Background: Oral squamous cell carcinoma is a common cancer of head and neck region with poor prognosis and may sometimes show a premalignant stage. Cell-cell adhesion molecules play an important role in the process of malignant transformation.
Dhanusree Kani, Vindhya Savithri, Rakesh Suresh, Ramanarayanan Venkitachalam, Mahija Janardhanan, Thara Aravind   +5 more
doaj   +2 more sources

Nucleostemin upregulation and STAT3 activation as early events in oral epithelial dysplasia progression to squamous cell carcinoma

Neoplasia: An International Journal for Oncology Research, 2021
Most low-grade oral epithelial dysplasia remains static or regress, but a significant minority of them (4–11%) advances to oral squamous cell carcinoma (OSCC) within a few years.
Madeleine Crawford, Xiaoqin Liu, Yi-Shing L Cheng, Robert YL Tsai   +3 more
doaj   +3 more sources

Assessment of apoptotic index in various grades of oral epithelial dysplasia: A cross-sectional study

Indian Journal of Pathology and Microbiology, 2020
Context: Oral cancer is a major health problem worldwide. In cancer, the equilibrium between cell proliferation and apoptosis is disturbed. The defect in the apoptotic pathway allows cells to proliferate with genetic abnormalities.
Rasika B Pawar, Sangeeta J Palaskar, Shravani S Kalavankar   +2 more
doaj   +1 more source

Expression of epithelial glycoprotein (EGP40) in oral epithelial dysplasia and oral squamous cell carcinoma (OSCC)

Indian Journal of Dental Research, 2020
Aim: To study the expression of Epithelial Glycoprotein (EGP40) in various grades of Oral Epithelial Dysplasia namely mild, moderate and severe epithelial dysplasia and in various grades of Oral Squamous Cell Carcinoma (OSCC) namely well, moderate & in ...
Kenniyan Kumar Srichinthu, G S Kumar, Harikrishnan Prasad, Muthusamy Rajmohan, Krishnamurthy Anuthama, Thuckanaickenpalayam Ragunathan Yoithapprabhunath   +5 more
doaj   +1 more source

Comparison of expression of myofibroblasts in normal oral mucosa, oral epithelial dysplasia, and oral squamous cell carcinoma using α-SMA and vimentin: An immunohistochemical study

Journal of Family Medicine and Primary Care, 2020
Background: Myofibroblasts are thought to play critical roles in inflammation, growth, repair, premalignancy, and malignancy. This study was done to evaluate, compare and co- relate the progressive increase in the immunohistochemical expression of ...
Amani Mahajan, Andleeb Manhas, Tania Aneja, Swati Parhar, Priyanka Kumari, Anubhuti, Harkanwal P Singh   +6 more
doaj   +1 more source

Analysis of Role of Angiogenesis in Epithelial Dysplasia: An Immunohistochemical Study [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Vascular Endothelial Growth Factor (VEGF) is an angiogenic cytokine which induces endothelial cell proliferation, migration and is important in developing new vascular beds.
Sonia Gupta, Vineeta Gupta, Nutan Tyagi, Ruchieka Vij, Hitesh Vij, Ettishree Sharma   +5 more
doaj   +1 more source

Oral epithelial dysplasia and aphthous ulceration in a patient with ulcerative colitis: a case report

BMC Oral Health, 2023
Background Ulcerative colitis is a chronic inflammatory disease with apparent extraintestinal manifestations, including in the oral cavity. Oral epithelial dysplasia, an exclusive histopathological diagnosis that is used to predict malignant ...
Kai Sun, Rong-Hui Xia
doaj   +1 more source

Role of Mast Cells in Progression of Oral Epithelial Dysplasia

RUHS Journal of Health Sciences, 2023
Introduction: Mast cells (MC) are the local residents of the connective tissue and are associated with the release of certain pro-inflammatory and mitogenic cytokines.
Shikha Saxena; Priyanka Singh; Akshay Bhargava; Krishna Sireesha Sundaragiri; Chandni Shekhawat; Bharat Sankhla
doaj   +1 more source

Suprabasal expression of Ki-67 as a marker for the severity of oral epithelial dysplasia and oral squamous cell carcinoma

Contemporary Clinical Dentistry, 2013
Background: Transition of the normal oral epithelium to dysplasia and to malignancy is featured by increased cell proliferation. To evaluate the hypothesis of distributional disturbances in proliferating and stem cells in oral epithelial dysplasia and ...
Nidhi Dwivedi, Shaleen Chandra, Bina Kashyap, Vineet Raj, Akhil Agarwal   +4 more
doaj   +1 more source