Results 41 to 50 of about 1,813,651 (244)

Assessment and Comparison of Cyclin D1 Expression in Different Histopathological Grades of Oral Epithelial Dysplasia - An In vitro Study

Indian Journal of Dental Research
Aim and Objectives: Quantitative evaluation and comparison of Cyclin D1 expression in various histological grades of oral epithelial dysplasia. Material and Methods: A total of 66 instances of oral epithelial dysplasia were included, with a histological ...
Sanjana Lingampalli, Kiran K. Kattappagari, Poosarla Chandrashekar, Vatsalya Kommalapati, Kantheti L. P. Chandra, Baddam V. R. Reddy   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

口腔粘膜の上皮性異形成におけるCK13, CK17, CK19, Ki 67, p53, p63, p21, p27 およびCyclin D1に関する免疫組織化学的検討 [PDF]

, 2023
大阪歯科大学Osaka Dental University博士（歯学）In the current World Health Organization (WHO) classification, oral epithelial dysplasia (OED) is classified using a two- or three-grade system.
キタヨシ, マリナ, 北吉, 麻理奈, Kitayoshi, Marina   +2 more
core   +1 more source

Immunohistochemical Analysis of PCNA and P53 Proteins in Oral Lichen Planus,Oral Dysplasia and Normal Oral Mucosa

Diyala Journal of Medicine, 2019
Background: The overexpression of the protein products of genes associated with the cell cycle protein p53 and PCNA is apparently of great significance. Oral lichen planus classified among the potentially malignant lesions of oral mucosa.
Lehadh M Al – Azzawi
doaj   +2 more sources

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Estudo de características clínicas e histopatológicas da queilite actínica e carcinoma epidermóide de lábio [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em OdontologiaA queilite actínica (QA) é uma doença potencialmente malignizável causada pela exposição solar crônica e excessiva.
Pilati, Sarah Freygang Mendes
core  

Diagnosis of differentiated dysplasia as a variant of oral epithelial dysplasia

Oral Diseases
AbstractObjectivesThe World Health Organization's definition of oral epithelial dysplasia includes differentiated dysplasia, which is defined by purely architectural abnormalities of oral mucosa without cytological changes. We analysed differentiated dysplasia's frequency, progression risk and correlation with oral brush cytology.Materials and ...
Anne‐Sophie Becker, Maximiliane Holm, Jan Liese, Nadja Engel, Annette Helene Zimpfer   +4 more
openaire   +2 more sources

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa [PDF]

, 2002
Background: Minichromosome maintenance (Mcm) proteins are essential for eukaryotic DNA replication, and their expression implies potential for cell proliferation.
Going, J.J., Keith, W.N., Stuart, RC, Stuart, R.C., Stoeber, K, Neilson, L, Stoeber, K., Williams, G.H., Williams, GH, Going, JJ, Keith, WN, Neilson, L.   +11 more
core   +1 more source