Results 61 to 70 of about 1,813,651 (244)

Voltage-Dependent Anion Channel 1 Expression in Oral Malignant and Premalignant Lesions

open access: yesDiagnostics, 2023
Background: The voltage-dependent anion channel 1 protein (VDAC1) plays a role in cellular metabolism and survival. It was found to be down or upregulated (overexpressed) in different malignancies but it was never studied in application to oral lesions ...
Irit Allon   +5 more
doaj   +1 more source

Urinary and Faecal Amino‐Acids as Biomarkers for Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT In Lynch syndrome, colonoscopy surveillance for colorectal cancer (CRC) is burdensome and post‐colonoscopy CRCs still occur. Unlike the faecal immunochemical test (FIT), gut metabolomic alterations including amino‐acids have shown potential as non‐invasive biomarkers for detecting both advanced and non‐advanced sporadic colorectal neoplasia ...
Roza C. M. Opperman   +18 more
wiley   +1 more source

Relationship of fibrosis and the expression of TGF-β1, MMP-1, and TIMP-1 with epithelial dysplasia in oral submucous fibrosis [PDF]

open access: yes, 2010
Background: Oral submucous fibrosis (OSF) is a premalignant fibrotic oral disease. The aim of this study was to investigate the relationship between fibrosis and the expression of TGF-β1, MMP-1, and TIMP-1 and epithelial dysplasia in OSF.
김진, 김기열
core   +1 more source

Effect of green propolis on oral epithelial dysplasia in rats [PDF]

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
Studies have demonstrated that flavonoid compounds of green propolis have antitumoral activity.Experimental study.To evaluate the effect of a hydroalcoholic extract of green propolis (EPV) on chemically induced epithelial dysplasias in rat tongues.DMBA was brushed on the lingual dorsum of rats 3x/week on alternate days--100 (PROP1), 200 (PROP2) and 300
Cavalcante, Danielle Rodrigues Ribeiro   +6 more
openaire   +4 more sources

Effect of tobacco, alcohol, and smoking habits in oral precancer with histological proven epithelial dysplasia

open access: yesJournal of Oral Biology and Craniofacial Research, 2012
Objectives: To assess the effect of risk factors tobacco, alcohol, and smoking habits in oral precancer patients with epithelial dysplasia status. Material and methods: The study sample included biopsy proven cases of 29 oral submucous fibrosis (OSMF ...
Seema Nayak   +6 more
doaj   +1 more source

Clearance of high‐risk human papillomavirus in patients with cervical intraepithelial neoplasia 2–3 after the loop electrosurgical excision procedure with negative resection margins

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aims to evaluate the longitudinal clearance rates of high‐risk human papillomavirus (hr‐HPV) and the incidence of clinical recurrence (defined by abnormal cytology or histologically confirmed cervical intraepithelial neoplasia; CIN) at 6 and 18 months post‐loop electrosurgical excision procedure (LEEP), characterizing the ...
Praew Sittichivapak, Pattama Chaopotong
wiley   +1 more source

HPV-16 in a distinct subset of oral epithelial dysplasia [PDF]

open access: yesModern Pathology, 2017
Human papillomavirus (HPV) 16 is the most common high-risk HPV type identified in oropharyngeal and cervical neoplasia. Recently, HPV-associated oral epithelial dysplasia with specific histopathologic features and demographics similar to HPV-oropharyngeal carcinoma has been identified. The objective of this study was to evaluate histopathologically all
Mark A, Lerman   +5 more
openaire   +2 more sources

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

The clinical determinants of malignant transformation in oral epithelial dysplasia [PDF]

open access: yesOral Oncology, 2012
While the size and clinical appearance are known risk factors for malignant transformation of potentially malignant oral the importance of site, grade of dysplasia and exposure to environmental carcinogens remains controversial. We aim to report the clinical determinants of malignant progression in a series of patients with histopathologically graded ...
Ho, M W   +10 more
openaire   +3 more sources

Morphometric analysis of suprabasal cell layer in oral epithelial dysplasia: A computer-assisted microscopic study

open access: yesJournal of Pharmacy and Bioallied Sciences, 2020
Background: Oral leukoplakia is the most common precancerous lesion. Various grading systems based on histological findings have been proposed for dysplasia.
Viswanathan Prema   +5 more
doaj   +1 more source

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