Aim: p53 and p63 are the important genes associated with oral cancer. The aim of this study was to evaluate and compare the immunohistochemical expression of p53 and p63 in oral epithelial dysplasia and squamous cell carcinoma (SCC).
Smitha Sammith Shetty +2 more
doaj +1 more source
Oral Epithelial Dysplasia and Premalignancy [PDF]
Leukoplakia and erythroplakia are two entities under the moniker of "oral potentially malignant disorders" that are highly associated with the presence of oral epithelial dysplasia (OED) at first biopsy, while lesions of submucous fibrosis develop OED after being present for years.
openaire +2 more sources
Diagnostic aids in the screening of oral cancer [PDF]
The World Health Organization has clearly indentified prevention and early detection as major objectives in the control of the oral cancer burden worldwide.
Fedele, S, Stefano Fedele
core +1 more source
LIHNCS - Lugol's iodine in head and neck cancer surgery : a multicentre, randomised controlled trial assessing the effectiveness of Lugol’s iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma : study protocol for a randomised controlled trial [PDF]
Background: Oral cavity and oropharynx cancer are increasing in incidence worldwide but survival outcomes have not significantly improved over the last three decades. The presence of dysplasia or carcinoma in situ at surgical margins following resection
McMahon, Jeremy +23 more
core +1 more source
Aim: To evaluate the expression of E-cadherin (E-cad) in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Material and Method: Immunohistochemistry was used to detect E-cad expression in 20 cases each of normal oral mucosa, oral ...
Jaishree Sharma +5 more
doaj +1 more source
The description of diagnosed cases of Oral Epithelial Dysplasia at the Tygerberg Oral Health Centre [PDF]
Magister Scientiae Dentium - MSc(Dent)Oral epithelial dysplasia (OED) is a growth anomaly which occurs as a result of atypical, abnormal proliferation and a change in the architecture and cytological features of cells of epithelial origin, which ...
Nkomo, Nocwaka
core +1 more source
The expression of Cathepsin L in oral lichen planus
Background: Malignant transformation of oral lichen planus (OLP) was reported particularly in erosive type, however, it remains inconclusive. Cathepsin L was shown to promote tumor growth and invasion in many cancers. Therefore, cathepsin L expression in
Athip Kitkhajornkiat +4 more
doaj +1 more source
The oral mycobiome: Oral epithelial dysplasia and oral squamous cell carcinoma
Abstract Fungi, a diverse group of eukaryotic organisms, play distinct roles in health and disease. Recent advances in the field of mycobiology have enabled the characterization of the “human mycobiome.” The human mycobiome has extensively been studied in various disease models.
Theofilou, V.I. +7 more
openaire +3 more sources
Expression of p63 in potentially malignant and malignant oral lesions
Background: p63, a member of p53 family, known to be expressed in embryonic tissues and basal regenerative layers of many epithelial tissues in the adult, is also expressed in various benign and malignant lesions of body including lesions of oral cavity.
Anju Sinha +5 more
doaj +1 more source
An Insight to Oral Epithelial Dysplasia
ABSTRACTOral dysplasia is a potentially precancerous lesion diagnosed histologically. While the risk of progression is associated with histological grade, it is currently impossible to predict accurately which lesions will progress. Although most oral pathologists recognize and accept the criteria for grading epithelial dysplasia based on architectural
Varun Rastogi +5 more
openaire +1 more source

