Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley +1 more source
ESMO Clinical Practice Guideline Express Update on the management of epithelial ovarian cancer. [PDF]
González-Martín A +2 more
europepmc +1 more source
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui +6 more
wiley +1 more source
Retraction: Exosome component 4 promotes epithelial ovarian cancer cell proliferation, migration, and invasion <i>via</i> the Wnt pathway. [PDF]
Frontiers Editorial Office.
europepmc +1 more source
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley +1 more source
A multi-channel fluorescence endoscope for pre-operative assessment of epithelial ovarian cancer. [PDF]
Pannem S +3 more
europepmc +1 more source
The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu +6 more
wiley +1 more source
Correction: Safety and efficacy of nab-paclitaxel combined with nedaplatin and bevacizumab in patients with platinum-resistant epithelial ovarian cancer: a retrospective cohort study. [PDF]
Li S +6 more
europepmc +1 more source
ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu +7 more
wiley +1 more source
Changes in Epithelial Ovarian Cancer Recurrence and Survival According to Treatment Paradigm Shifts. [PDF]
Kim J, Suh DH, Kim K, No JH, Kim YB.
europepmc +1 more source

